[Immunological studies of aging and the family in gastric cancer, with special reference to cell-medical immunity].

Cell-mediated immunity of the aging and immune response in the family of gastric cancer have been investigated and the following results were obtained. Immune response particularly of cell-mediated immunity was found decreased in paralled with aging; decreases in peripheral lymphocyte and T-cell counts, rate of Con A and PHA induced blastoid transformation, and the tendency of increase in suppressor T-cell were noted. Investigations on the immune response in the family of gastric cancer revealed that cell-mediated immune response was recreased in the compared to age-matched healthy volunteers. These findings suggest that latent immunological failure may exist in the above family.