Belov D F, Nikolaenko V P
Saint Petersburg Multifield Hospital No. 2, St. Petersburg, Russia.
Saint Petersburg State University, St. Petersburg, Russia.
Vestn Oftalmol. 2021;137(6):61-66. doi: 10.17116/oftalma202113706161.
To assess biometric changes in eyes after trabeculectomy (TE) and its impact on refractive outcomes of phacoemulsification (PE) in order to determine the corrections for calculation of intraocular lens (IOL) power.
The study included two groups of patients: the 1 group consisted of 116 patients who were assessed by optical biometry (IOL-Master 500) for mean biometric values before and after TE; the 2 group included 31 patients with history of TE (study subgroup) and 47 individuals without glaucoma (control subgroup) who underwent PE with subsequent comparison of IOL calculation accuracy.
There was significant axial length (AL) shortening in the 1 group from 23.28±0.97 to 23.19±0.97 mm (<0.001) 6 months after TE, which positively correlated (=0.296, =0.001) with intraocular pressure (IOP) decrease (from 25.4±5.34 to 17.2±4.42 mm Hg, <0.001). Mean keratometry and anterior chamber depth values did not significantly change after TE. Mean IOL power calculation error after PE in the 2 group was -0.05±0.47 D and 0.003±0.62 D for the control and study subgroups, respectively (=0.697). However, significant impact of preoperative IOP on IOL power calculation error was discovered in the study subgroup (R=0.526, <0.001), but not in the control subgroup (R=0.061, =0.052). Based on linear regression, the expected IOL power calculation errors depending on the preoperative IOP were determined for patients with history of TE.
AL shortening due to decrease in IOP in patients with history of TE leads to IOL power calculation errors. Expected IOL calculation error related to preoperative IOP level was determined, which could help improve refractive outcomes of PE in patients with history of TE.
评估小梁切除术(TE)后眼睛的生物测量变化及其对白内障超声乳化术(PE)屈光结果的影响,以确定人工晶状体(IOL)屈光力计算的校正值。
该研究包括两组患者:第1组由116例患者组成,通过光学生物测量法(IOL-Master 500)评估TE前后的平均生物测量值;第2组包括31例有TE病史的患者(研究亚组)和47例无青光眼的个体(对照亚组),他们接受了PE手术,随后比较IOL计算准确性。
第1组在TE后6个月时眼轴长度(AL)显著缩短,从23.28±0.97 mm降至23.19±0.97 mm(P<0.001),这与眼压(IOP)降低呈正相关(r=0.296,P=0.001)(眼压从25.4±5.34 mmHg降至17.2±4.42 mmHg,P<0.001)。TE后平均角膜曲率和前房深度值无显著变化。第2组中,对照亚组和研究亚组在PE后的平均IOL屈光力计算误差分别为-0.05±0.47 D和0.003±0.62 D(P=0.697)。然而,在研究亚组中发现术前IOP对IOL屈光力计算误差有显著影响(R=0.526,P<0.001),而在对照亚组中未发现(R=0.061,P=0.052)。基于线性回归,确定了有TE病史患者根据术前IOP的预期IOL屈光力计算误差。
有TE病史患者因IOP降低导致的AL缩短会引起IOL屈光力计算误差。确定了与术前IOP水平相关的预期IOL计算误差,这有助于改善有TE病史患者的PE屈光结果。