Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok Road, Bangkok, 10700, Thailand.
Graefes Arch Clin Exp Ophthalmol. 2019 Dec;257(12):2677-2682. doi: 10.1007/s00417-019-04443-7. Epub 2019 Sep 5.
To compare the refractive outcomes following cataract surgery using conventional keratometry (K) and total keratometry (TK) for intraocular lens (IOL) calculation in the SRK/T, HofferQ, Haigis, and Holladay 1 and 2, as well as Barrett and Barrett TK Universal II formulas.
Sixty eyes of 60 patients from Siriraj Hospital, Thailand, were prospectively enrolled in this comparative study. Eyes were assessed using a swept-source optical biometer (IOLMaster 700; Carl Zeiss Meditec, Jena, Germany). Posterior keratometry, K, TK, central corneal thickness, anterior chamber depth, lens thickness, axial length, and white-to-white corneal diameter were recorded. Emmetropic IOL power was calculated using K and TK in all formulas. Selected IOL power and predicted refractive outcomes were recorded. Postoperative manifest refraction was measured 3 months postoperatively. Mean absolute errors (MAEs), median absolute errors (MedAEs), and percentage of eyes within ± 0.25, ± 0.50, and ± 1.00 D of predicted refraction were calculated for all formulas in both groups.
Mean difference between K and TK was 0.03 D (44.56 ± 1.18 vs. 44.59 ± 1.22 D), showing excellent agreement (ICC = 0.99, all p < 0.001). Emmetropic IOL powers in all formulas for both groups were very similar, with a trend toward lower MAEs and MedAEs for TK when compared with K. The Barrett TK Universal II formula demonstrated the lowest MAEs. Proportion of eyes within ± 0.25, ± 0.50, and ± 1.00 D of predicted refraction were slightly higher in the TK group.
Conventional K and TK for IOL calculation showed strong agreement with a trend toward better refractive outcomes using TK. The same IOL constant can be used for both K and TK.
比较在 SRK/T、HofferQ、Haigis、Holladay 1 和 2 以及 Barrett 和 Barrett TK Universal II 公式中,使用常规角膜曲率计 (K) 和总角膜曲率计 (TK) 计算人工晶状体 (IOL) 时的术后屈光度。
本前瞻性研究纳入了 60 例(60 只眼)来自泰国诗里拉吉医院的患者。使用扫频源光学生物测量仪(IOLMaster 700;卡尔蔡司医疗技术公司,耶拿,德国)评估眼。记录后角膜曲率、K、TK、中央角膜厚度、前房深度、晶状体厚度、眼轴长度和角膜白到白直径。在所有公式中均使用 K 和 TK 计算出正视眼的 IOL 屈光力。记录所选 IOL 屈光力和预测屈光结果。术后 3 个月测量术后客观验光。计算所有公式在两组中的平均绝对误差 (MAE)、中位数绝对误差 (MedAE) 和预测屈光度在 ± 0.25、± 0.50 和 ± 1.00 D 范围内的眼数百分比。
K 和 TK 之间的平均差异为 0.03 D(44.56 ± 1.18 与 44.59 ± 1.22 D),显示出极好的一致性(ICC 分别为 0.99,所有 p 值均<0.001)。两组所有公式的正视眼 IOL 屈光力非常相似,与 K 相比,TK 具有更低的 MAE 和 MedAE 的趋势。Barrett TK Universal II 公式显示出最低的 MAE。TK 组预测屈光度在 ± 0.25、± 0.50 和 ± 1.00 D 范围内的眼数比例略高。
常规 K 和 TK 用于 IOL 计算具有很强的一致性,使用 TK 有更好的屈光效果趋势。可以为 K 和 TK 使用相同的 IOL 常数。