Emergency Department of Fuling Central Hospital, No. 2 Gaosuntang Road, Fuling District, Chongqing 408099, China.
Corresponding author.
Discov Med. 2021 Mar-Apr;31(163):61-68.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a global crisis due to strong infectivity and fast transmission speed. Some patients with Coronavirus Disease 2019 (COVID-19) progress rapidly and may develop fatal complications, which brings serious challenges in disease assessment and treatment. Recent progress in the understanding of the molecular biology of SARS-CoV-2 has led to the identification of a variety of laboratory biomarkers that could be potentially applied to clinical practice for the diagnosis, treatment, and prognosis of patients with COVID-19. In this review we summarize the updated status on the identification of COVID-19 related laboratory markers, and propose further direction on the application of these markers to clinical diagnosis and management of patients with COVID-19.
严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）由于其较强的传染性和快速传播速度已成为全球性危机。一些 2019 年冠状病毒病（COVID-19）患者病情迅速进展，可能发生致命并发症，这给疾病评估和治疗带来了严峻挑战。对 SARS-CoV-2 分子生物学的最新认识，使得各种实验室生物标志物得以鉴定，这些标志物可能应用于 COVID-19 患者的临床诊断、治疗和预后。本综述总结了 COVID-19 相关实验室标志物鉴定的最新进展，并就这些标志物在 COVID-19 患者临床诊断和管理中的应用提出了进一步的方向。
