Women's Hospital, Zhejiang University School of Medicine, 1 Xueshi Road, Hangzhou, 310006, Zhejiang Province, People's Republic of China.
Maternal and Child Health Institute of Zhejiang, Linan City, People's Republic of China.
BMC Womens Health. 2021 Dec 29;21(1):436. doi: 10.1186/s12905-021-01542-8.
This study aimed to estimate the difference in vaginal bleeding pattern, discontinuation rate, and satisfaction between immediate after abortion and menstrual insertions of etonogestrel contraceptive implants.
Between May 2013 and November 2015, 66 women were recruited in the abortion group who selected etonogestrel implants as their contraceptive immediately after induced abortion. 84 women who underwent the placement of the etonogestrel implant during their menstrual period were enrolled as the menstrual group. The two groups participated in 3-year follow-up outpatient visits at 1, 6, 12, 24, and 36 months after implantation. The vaginal bleeding pattern, discontinuation rate, satisfaction rate were recorded and compared.
No woman had pregnancy over the study period of 3 years. The incidence of amenorrhea/infrequent bleeding did not differ between the two groups after 12, 24, and 36 months of implantation (53.0% vs. 58.4%, 47.8% vs. 51.6%, and 48.6% vs. 55.6%, respectively). In the abortion group, the incidences of frequent/prolonged bleeding were 15.1%, 32.6%, and 27.0% after 12, 24, and 36 months of implantation, respectively, while the other group showed 27.3%, 25.8%, and 20.4%, respectively. After 12 and 24 months, the continuation use rates were 69.7% and 56.1% in the abortion group and 73.8% and 64.2% in the menstrual group. The 12-month satisfaction rate between abortion group and menstrual group was 69.6% versus 72.6%. Statistical analyses show that there was no difference in vaginal bleeding pattern, discontinuation rate or satisfaction between the two groups.
Immediately post-abortion may be also a favorable time to undergo etonogestrel implantation.
本研究旨在评估依伴侬皮下埋植剂即刻放置与月经周期放置的阴道出血模式、停药率和满意度差异。
2013 年 5 月至 2015 年 11 月,选择依伴侬皮下埋植剂作为流产后即时避孕方法的 66 例妇女纳入流产组。同期选择在月经周期放置依伴侬皮下埋植剂的 84 例妇女纳入月经组。两组均在植入后 1、6、12、24 和 36 个月进行 3 年的门诊随访。记录并比较两组的阴道出血模式、停药率和满意度。
研究期间,两组均无妊娠。植入后 12、24 和 36 个月时,两组闭经/经量减少的发生率无差异(53.0%比 58.4%、47.8%比 51.6%、48.6%比 55.6%)。流产组在植入后 12、24 和 36 个月时频繁/延长出血的发生率分别为 15.1%、32.6%和 27.0%,而月经组分别为 27.3%、25.8%和 20.4%。植入后 12 和 24 个月,流产组的继续使用率为 69.7%和 56.1%,月经组分别为 73.8%和 64.2%。流产组和月经组在 12 个月时的满意度分别为 69.6%和 72.6%。统计学分析显示,两组间阴道出血模式、停药率或满意度无差异。
即时流产后也可作为依伴侬皮下埋植剂的有利放置时机。