Author Affiliations: School of Nursing, Virginia Commonwealth University (Drs Ameringer and Elswick Jr.), Richmond; Children's Mercy Hospital (Dr Stegenga), Kansas City, Missouri; Seattle Children's Hospital (Dr Macpherson), Seattle, Washington; College of Nursing, University of Wisconsin-Milwaukee (Dr Erickson); and University of Utah College of Nursing and Primary Children's Hospital, Salt Lake City (Dr Linder).
Cancer Nurs. 2022;45(4):306-315. doi: 10.1097/NCC.0000000000001047. Epub 2021 Dec 29.
The symptom experience of adolescents and young adults (AYAs) with cancer can differ based on the cancer and its treatments. A dearth of information exists on how symptoms differ by individual factors such as age and gender.
The objectives were to describe symptoms in AYAs across 5 cancer diagnostic groups by the individual factors of age group, sex, race/ethnicity, and time since diagnosis; and then to describe symptoms based on these individual factors within diagnostic groups.
This was a secondary analysis of baseline data pooled from 2 multisite studies on symptoms in AYAs with acute lymphoblastic leukemia, brain cancer, Hodgkin lymphoma, non-Hodgkin lymphoma, and sarcoma. Symptoms were assessed using the Computerized Symptom Capture Tool.
Data from 118 AYAs with cancer, aged 13 to 29 years, were analyzed. Eight of the most commonly reported symptoms were reported in at least 4 diagnostic groups. Across diagnostic groups, symptoms varied little based on individual factors. Within groups, certain symptoms differed in frequency by individual factors.
The lack of major differences in symptom prevalence based on individual factors across diagnostic groups supports a heterogeneous approach to symptom research with AYAs. The study identified individual factors within diagnostic groups worthy of further exploration.
Providers can facilitate discussions with AYAs about symptoms by being aware of common symptoms that may occur in certain cancer diagnostic groups and based on individual factors. The significance of the individual symptom experience should not be underestimated, emphasizing the importance of person-centered symptom assessment.
青少年和年轻成人（AYA）的癌症症状体验可能因癌症及其治疗方法而异。关于症状如何因年龄和性别等个体因素而有所不同的信息很少。
本研究的目的是通过年龄组、性别、种族/民族和诊断后时间等个体因素描述 5 个癌症诊断组中 AYA 的症状，并根据这些个体因素在诊断组内描述症状。
这是对 2 项关于急性淋巴细胞白血病、脑癌、霍奇金淋巴瘤、非霍奇金淋巴瘤和肉瘤中 AYA 症状的多中心研究的基线数据进行的二次分析。使用计算机化症状采集工具评估症状。
分析了来自 118 名年龄在 13 至 29 岁之间的癌症 AYA 的数据。至少有 4 个诊断组报告了 8 种最常见的症状。在不同的诊断组中，症状在很大程度上不受个体因素的影响。在各诊断组内，某些症状在频率上因个体因素而异。
个体因素在各诊断组之间的症状流行率差异不大，这支持了对 AYA 进行症状研究的异质方法。该研究确定了各诊断组内值得进一步探索的个体因素。
提供者可以通过了解可能在某些癌症诊断组中发生的常见症状以及基于个体因素，促进与 AYA 就症状进行讨论。不应低估个体症状体验的重要性，强调以患者为中心的症状评估的重要性。
