Müller S
Z Erkr Atmungsorgane. 1987;168(2):114-25.
Current research results on the bronchoalveolar lavage (BAL) fluid of patients with extrinsic allergic alveolitis (EAA) are represented in a survey. The method of BAL, the preparation of the BAL-fluid, the differential cell count, the differentiation of lymphocytes, the determination of metabolic activity of alveolar macrophages and of the humoral components are described. The elevated total cell number, the relative and absolute increase of the total and T-lymphocyte number, the raised total protein content and the increased activity of T-lymphocytes and macrophages are characteristic features of the BAL-fluid in EAA. The possible significance of these changes for the pathogenesis of EAA and the problem of the so-called sensitized asymptomatics are discussed.
一项调查展示了目前关于外源性过敏性肺泡炎(EAA)患者支气管肺泡灌洗(BAL)液的研究结果。描述了BAL的方法、BAL液的制备、细胞分类计数、淋巴细胞分化、肺泡巨噬细胞代谢活性及体液成分的测定。EAA患者BAL液的特征性表现为细胞总数升高、总淋巴细胞及T淋巴细胞数量的相对和绝对增加、总蛋白含量升高以及T淋巴细胞和巨噬细胞活性增强。讨论了这些变化对EAA发病机制的可能意义以及所谓致敏无症状者的问题。