University of Pisa, Pisa 56127, Italy.
Exp Oncol. 2021 Dec;43(4):376-378. doi: 10.32471/exp-oncology.2312-8852.vol-43-no-4.17026.
Primary cutaneous follicle center lymphoma (PCFCL) is a rare low-grade cutaneous B-cell lymphoma. Clinically, PCFCL is usually an erythematous subcutaneous nodule or an infiltrated plaque. The dermoscopy is non-specific and it is characterized by polymorphous vascular pattern, arborizing vessels over a salmon-colored background and white areas. We reported a case of a 36-year-old woman presented with a rapidly growing, flashed-color, exophytic, soft consistency nodule on her scalp. Dermoscopy showed a diffuse structureless, skin-color area associated with a rare arborizing vascular pattern and brown circles. We reported a peculiar clinical and dermoscopic variant. This clinical presentation of PCFCL is unusual and represents a pitfall in the early clinical diagnosis. Histopathology is mandatory for a correct diagnosis.
原发性皮肤滤泡中心淋巴瘤(PCFCL)是一种罕见的低度皮肤 B 细胞淋巴瘤。临床上,PCFCL 通常为红斑性皮下结节或浸润性斑块。其皮肤镜表现是非特异性的,特征为多形性血管模式、鲑鱼色背景上的树枝状血管和白色区域。我们报告了一例 36 岁女性病例,其头皮上出现快速生长、闪光颜色、外生性、柔软质地的结节。皮肤镜显示弥漫性无结构、肤色区域,伴有罕见的树枝状血管模式和棕色圆圈。我们报告了一种特殊的临床和皮肤镜变异型。PCFCL 的这种临床表现不常见,是早期临床诊断的一个陷阱。组织病理学检查对于正确诊断是必需的。