Mascolo Massimo, Piccolo Vincenzo, Argenziano Giuseppe, Costa Claudia, Lo Presti Maurizio, De Rosa Gaetano, Scalvenzi Massimiliano, Staibano Stefania
Pathology Section, Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Dermatology. 2016;232(2):203-7. doi: 10.1159/000442251. Epub 2015 Dec 23.
To date, no dermoscopic features have been described for the diagnosis of primary cutaneous B-cell lymphoma (PCBCL). This tool might be helpful for the clinical differential diagnosis in the context of single erythematous nodules of the skin.
Ten cases of PCBCL, presenting clinically as solitary red/pinkish nodules, were retrospectively retrieved. Patient data were collected along with dermoscopic and histopathological features of each lesion. Most lesions (9/10) showed white circles with a salmon-colored background/area (6 lesions), scales (7 lesions), arborizing vessels (5 lesions) or a polymorphous vascular pattern (2 lesions). Histology revealed a cutaneous marginal zone lymphoma in 6 lesions, a follicle center lymphoma in 2 lesions and a diffuse large B-cell lymphoma in 2 lesions.
Dermoscopic examination may be helpful for improving the clinical recognition of PCBCL although skin biopsy remains mandatory.
迄今为止，尚未有用于诊断原发性皮肤B细胞淋巴瘤（PCBCL）的皮肤镜特征被描述。在皮肤单个红斑结节的情况下，该工具可能有助于临床鉴别诊断。
回顾性检索了10例临床上表现为孤立性红色/粉红色结节的PCBCL病例。收集了患者数据以及每个病变的皮肤镜和组织病理学特征。大多数病变（9/10）表现为白色圆圈，背景/区域呈鲑鱼色（6个病变）、鳞屑（7个病变）、树枝状血管（5个病变）或多形性血管模式（2个病变）。组织学显示6个病变为皮肤边缘区淋巴瘤，2个病变为滤泡中心淋巴瘤，2个病变为弥漫性大B细胞淋巴瘤。
皮肤镜检查可能有助于提高对PCBCL的临床识别，尽管皮肤活检仍然是必需的。
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