Manuelidis E E, Gorgacs E J, Manuelidis L
Science. 1978 Jun 2;200(4345):1069-71. doi: 10.1126/science.349691.
Inoculation of the buffy coat of blood from guinea pigs infected with Creutzfeldt-Jakob disease resulted in passage of this disease to recipient animals. This demonstrates that there is a viremia in experimental Creutzfeldt-Jakob disease. These findings suggest that the hematogenous route may be implicated in the human infection and that the disease may possibly be transmitted by blood transfusions.
将感染克雅氏病的豚鼠血液中的血沉棕黄层接种到受体动物身上，导致该病在受体动物中传播。这表明在实验性克雅氏病中存在病毒血症。这些发现提示血行途径可能与人类感染有关，并且该病可能通过输血传播。
