匈牙利一项回顾性研究：口腔癌患者的糖尿病和空腹血糖受损患病率。

Prevalence of Diabetes and Impaired Fasting Glycemia in Patients With Oral Cancer: A Retrospective Study in Hungary.

机构信息

Department of Maxillofacial and Oral Surgery, Semmelweis University, Budapest, Hungary.

Diabetes-Dental Working Group, Semmelweis University, Budapest, Hungary.

出版信息

Anticancer Res. 2022 Jan;42(1):109-113. doi: 10.21873/anticanres.15464.

DOI:10.21873/anticanres.15464

PMID:34969716

Abstract

BACKGROUND/AIM: Diabetes mellitus (DM) is one of the most common chronic metabolic disorders. Our research aimed to demonstrate the relationship between DM and oral cancer.

PATIENTS AND METHODS

We pursued a retrospective research study in Hungary between January 2019 and December 2020. We investigated 597 inpatient records and compared them to the results of our previous studies (1998-2002 and 2012-2015).

RESULTS

The frequency of patients with DM in the oral cancer group is 2.45 times higher today than 20 years ago. The prevalence rate of DM and oral malignancies increased from 14.6% to 35.8%. In the oral cancer group, 54.4% of the patients had elevated blood glucose levels and of these, 61.1% of them had type 2 diabetes, 34.2% had impaired fasting glycemia, and only 4.7% had type 1 diabetes. We observed that 45.3% of them were smokers. Of those whose blood sugar levels were under 6.1 mmol/l, the mean body mass index was 25.33 [standard deviation (SD)=±4.5; range=15.57-39.84], while among patients with DM, it was 26.92 (SD=±5.8; range=18.36-44.08).

CONCLUSION

It may be necessary to continuously monitor the patient's blood sugar level to maintain euglycemic levels when managing patients with malignant oral lesions.

摘要

背景/目的：糖尿病（DM）是最常见的慢性代谢紊乱之一。我们的研究旨在证明 DM 与口腔癌之间的关系。

患者和方法

我们在 2019 年 1 月至 2020 年 12 月期间在匈牙利进行了一项回顾性研究。我们调查了 597 名住院患者的记录，并将其结果与我们之前的研究（1998-2002 年和 2012-2015 年）进行了比较。

结果

如今，患有 DM 的口腔癌患者的频率比 20 年前高 2.45 倍。DM 和口腔恶性肿瘤的患病率从 14.6%增加到 35.8%。在口腔癌组中，54.4%的患者血糖升高，其中 61.1%为 2 型糖尿病，34.2%为空腹血糖受损，只有 4.7%为 1 型糖尿病。我们观察到 45.3%的患者吸烟。在血糖水平低于 6.1mmol/l 的患者中，平均体重指数为 25.33（标准差[SD]=±4.5；范围=15.57-39.84），而在 DM 患者中，为 26.92（SD=±5.8；范围=18.36-44.08）。