Department of Oral and Maxillofacial Surgery, University Clinic of Dental Medicine and Oral Health, Medical University Graz, Graz, Austria.
Department of Oral Surgery and Orthodontics, University Clinic of Dental Medicine and Oral Health, Medical University Graz, Graz, Austria.
Anticancer Res. 2022 Apr;42(4):1899-1903. doi: 10.21873/anticanres.15666.
This study aimed to analyse the possible linkage between diabetes mellitus (DM) and oral cancer among Austrians.
We performed a retrospective DM and/or impaired fasting glucose (IFG) screening in 573 patients who underwent maxillofacial surgery under general anaesthesia between January 1, 2018 and December 31, 2019.
Of the total patients, 26.5% (n=152) had cancer diagnosis, whereas the remaining 73.5% (n=421) formed the control group. The prevalence of glucose metabolism disorder (GMD) was significantly (p<0.00001) more common among cancer patients (59.9% vs. 36.5%). Squamous cell carcinoma and sublingual tumours represented the most common tumour type (93.4%) and location (35.5%), respectively. Smoking was significantly (p=0.00093) more common within the cancer group.
Our data suggest an association between GMD and oral cancer.
本研究旨在分析奥地利人群中糖尿病（DM）与口腔癌之间可能存在的关联。
我们对 2018 年 1 月 1 日至 2019 年 12 月 31 日期间在全身麻醉下接受颌面外科手术的 573 名患者进行了回顾性 DM 和/或空腹血糖受损（IFG）筛查。
在总患者中，26.5%（n=152）有癌症诊断，而其余 73.5%（n=421）为对照组。癌症患者中葡萄糖代谢紊乱（GMD）的患病率明显更高（59.9%比 36.5%）（p<0.00001）。鳞状细胞癌和舌下肿瘤分别是最常见的肿瘤类型（93.4%）和位置（35.5%）。癌症组中吸烟明显更常见（p=0.00093）。
我们的数据表明 GMD 与口腔癌之间存在关联。
