Improving Assessment of Disease Severity and Strategies for Monitoring Progression in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 4].
作者信息
Tetreault Lindsay, Garwood Philip, Gharooni Aref-Ali, Touzet Alvaro Yanez, Nanna-Lohkamp Laura, Martin Allan, Wilson Jefferson, Harrop James S, Guest James, Kwon Brian K, Milligan James, Arizala Alberto Martinez, Riew K Daniel, Fehlings Michael G, Kotter Mark R N, Kalsi-Ryan Sukhvinder, Davies Benjamin M
机构信息
Department of Neurology, Langone Health, Graduate Medical Education, 5894New York University, New York, NY, USA.
Graduate Medical Education, Internal Medicine, 7938University of Toronto, Toronto, ON, Canada.
出版信息
Global Spine J. 2022 Feb;12(1_suppl):64S-77S. doi: 10.1177/21925682211063854. Epub 2021 Dec 31.
STUDY DESIGN
Narrative Review.
OBJECTIVE
To (i) discuss why assessment and monitoring of disease progression is critical in Degenerative cervical myelopathy (DCM); (ii) outline the important features of an ideal assessment tool and (iii) discuss current and novel strategies for detecting subtle deterioration in DCM.
METHODS
Literature review.
RESULTS
Degenerative cervical myelopathy is an overarching term used to describe progressive injury to the cervical spinal cord by age-related changes of the spinal axis. Based on a study by Smith et al (2020), the prevalence of DCM is approximately 2.3% and is expected to rise as the global population ages. Given the global impact of this disease, it is essential to address important knowledge gaps and prioritize areas for future investigation. As part of the AO Spine RECODE-DCM (Research Objectives and Common Data Elements for Degenerative Cervical Myelopathy) project, a priority setting partnership was initiated to increase research efficiency by identifying the top ten research priorities for DCM. One of the top ten priorities for future DCM research was: What assessment tools can be used to evaluate functional impairment, disability and quality of life in people with DCM? What instruments, tools or methods can be used or developed to monitor people with DCM for disease progression or improvement either before or after surgical treatment?
CONCLUSIONS
With the increasing prevalence of DCM, effective surveillance of this population will require both the implementation of a monitoring framework as well as the development of new assessment tools.
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