Vo Duy Quoc, Zhang Lu, Noguchi Naoto, Kondo Ken, Akiyama Ryoto, Fujii Hiroshi, Obokata Yuki, Lee Bumsuk
Gunma University Graduate School of Health Sciences Doctoral Program, Maebashi, Gunma, Japan.
Gunma University Graduate School of Health Sciences, Maebashi, Gunma, Japan.
PLoS One. 2025 Aug 1;20(8):e0328197. doi: 10.1371/journal.pone.0328197. eCollection 2025.
The aim of this study was to kinetically evaluate the changes in precision grip in patients with degenerative cervical myelopathy before and after decompressive surgery.
Twenty-nine patients with degenerative cervical myelopathy participated in the study. Participants performed a grip-and-lift task by pulp pinch using their thumb and index finger before and after surgery. We monitored individual finger grip force (GF) and center of pressure (COP) trajectory in total five seconds and during the first second while lifting and holding an object. Correlations between the pre-operative COP trajectory and other hand clinical outcomes were analyzed. A multiple regression analysis was used to identify the predictive value of the pre-operative COP trajectory to the severity of sensorimotor dysfunction.
There was a significant improvement in the 1-second COP trajectory in the index finger after surgery, but not the GF. Moreover, pre-operative COP trajectory was associated with the post-operative severity of clinical symptoms. The multiple regression analysis concerning the severity of upper extremity symptoms indicated that the model incorporating pre-operative COP trajectory exhibited the highest adjusted R2 compared to GF or conventional clinical tests.
These results suggested that patients with degenerative cervical myelopathy could improve their COP trajectory in the index finger after surgery, and the finger kinetic measure could provide an important index for predicting neurological improvement.
本研究旨在动态评估退行性颈椎病患者减压手术前后精确抓握能力的变化。
29例退行性颈椎病患者参与本研究。参与者在手术前后用拇指和示指通过指尖捏的方式执行抓握和提起任务。我们在总共五秒内以及提起和握住物体的第一秒内监测了各个手指的握力（GF）和压力中心（COP）轨迹。分析术前COP轨迹与其他手部临床结果之间的相关性。采用多元回归分析确定术前COP轨迹对感觉运动功能障碍严重程度的预测价值。
术后示指1秒COP轨迹有显著改善，但握力无改善。此外，术前COP轨迹与术后临床症状严重程度相关。关于上肢症状严重程度的多元回归分析表明，与握力或传统临床测试相比，纳入术前COP轨迹的模型显示出最高的调整R2。
这些结果表明，退行性颈椎病患者术后示指的COP轨迹可得到改善，手指动力学测量可为预测神经功能改善提供重要指标。
