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重症监护中的预防性氢氧化铝与高铝血症

Prophylactic aluminium hydroxide and hyperaluminaemia in intensive care.

作者信息

Mackway-Jones K, Cove-Smith R, Lawler P

出版信息

Intensive Care Med. 1987;13(4):293-4. doi: 10.1007/BF00265122.

DOI:10.1007/BF00265122
PMID:3497185
Abstract

Prophylactic antacid therapy is widely used in intensive care units. We show that significant hyperaluminaemia may occur during the course of prophylaxis with aluminium hydroxide in patients with compromised renal function. Since a significant proportion of patients in intensive care have, or are at risk of developing, renal failure we suggest that the routine use of aluminium hydroxide should be avoided.

摘要

预防性抗酸治疗在重症监护病房中广泛使用。我们发现,肾功能受损的患者在使用氢氧化铝进行预防治疗过程中可能会出现明显的高铝血症。由于重症监护病房中有相当一部分患者已经存在肾功能衰竭或有发生肾功能衰竭的风险,我们建议应避免常规使用氢氧化铝。

相似文献

1
Prophylactic aluminium hydroxide and hyperaluminaemia in intensive care.重症监护中的预防性氢氧化铝与高铝血症
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2
Hyperaluminaemia in critically ill patients: role of antacid therapy and impaired renal function.危重症患者的高铝血症:抗酸治疗及肾功能受损的作用
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Prophylactic aluminium hydroxide and hyperaluminaemia in intensive care.重症监护中的预防性氢氧化铝与高铝血症
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引用本文的文献

1
Prophylactic aluminium hydroxide and hyperaluminaemia in intensive care.重症监护中的预防性氢氧化铝与高铝血症
Intensive Care Med. 1988;14(4):445-6. doi: 10.1007/BF00262911.
2
Serum aluminium levels of intensive care patients treated with two different antacids for prevention of stress ulceration.使用两种不同抗酸剂预防应激性溃疡的重症监护患者的血清铝水平。
Intensive Care Med. 1989;15(2):84-6. doi: 10.1007/BF00295982.

本文引用的文献

1
International Workshop on the role of biological monitoring in the prevention of aluminium toxicity in man: "Aluminium Analysis in Biological Fluids," Luxembourg, July 5-7, 1982. Memorandum on the summary and conclusions.
J Toxicol Clin Toxicol. 1982 Oct;19(8):907-10. doi: 10.3109/15563658208992524.
2
Antacid versus cimetidine in preventing acute gastrointestinal bleeding. A randomized trial in 75 critically ill patients.抗酸剂与西咪替丁预防急性胃肠道出血的比较。一项针对75例危重症患者的随机试验。
N Engl J Med. 1980 Feb 21;302(8):426-30. doi: 10.1056/NEJM198002213020802.
3
Antacid versus sucralfate in preventing acute gastrointestinal bleeding. A randomized trial in 100 critically ill patients.
Am J Surg. 1984 Dec;148(6):809-12. doi: 10.1016/0002-9610(84)90443-4.
4
Serum aluminium measurements in renal bone disease.肾性骨病中的血清铝测定
Lancet. 1983 May 21;1(8334):1168-9.
5
Antacid titration in the prevention of acute gastrointestinal bleeding: a controlled, randomized trial in 100 critically ill patients.
N Engl J Med. 1978 May 11;298(19):1041-5. doi: 10.1056/NEJM197805112981901.