Tc-MAG 肾动态显像评估个体肾功能。
Assessment of Individual Renal Function Using Tc-MAG Renography.
机构信息
College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.
College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
出版信息
In Vivo. 2022 Jan-Feb;36(1):206-211. doi: 10.21873/invivo.12692.
BACKGROUND/AIM: This study performed Tc-MAG renal scintigraphy on rabbit kidneys and evaluated its ability to identify obstructive or non-obstructive kidneys.
MATERIALS AND METHODS
Renal function was assessed during a four-week post-obstruction period by obtaining planar images of Tc-MAG activity following an ear vein injection. The individual renal function was evaluated by renal scintigraphy in conjunction with histopathological and morphological examinations.
RESULTS
The renal perfusion of Tc-MAG in the right kidney with a ureteral obstruction decreased with time. The width, height, and cortical thickness of the obstructed right kidney were significantly larger than those of the left kidney. A histopathological examination four weeks after the ureteral obstruction revealed a typical pattern of urinary tract obstruction, including multiple tubules, enlargement of the interstitial area, and cytoplasmic vacuoles.
CONCLUSION
Tc-MAG renal scintigraphy provides the kidney shape and size and can identify potential obstructive and non-obstructive kidneys in rabbits.
背景/目的：本研究对兔肾进行 Tc-MAG 肾闪烁显像，并评估其识别梗阻性或非梗阻性肾脏的能力。
材料与方法
在梗阻后 4 周期间，通过经耳静脉注射 Tc-MAG 活性后获得平面图像来评估肾功能。通过肾闪烁显像与组织病理学和形态学检查相结合来评估个体肾功能。
结果
右侧输尿管梗阻的 Tc-MAG 肾灌注随时间推移而减少。梗阻右侧肾脏的宽度、高度和皮质厚度明显大于左侧肾脏。输尿管梗阻 4 周后的组织病理学检查显示出典型的尿路梗阻模式，包括多个肾小管、间质区增大和细胞质空泡。
结论
Tc-MAG 肾闪烁显像可提供肾脏的形状和大小，并可识别兔的潜在梗阻性和非梗阻性肾脏。
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