降低直肠癌手术患者手术部位感染率的干预策略。
Intervention Strategies to Reduce Surgical Site Infection Rates in Patients Undergoing Rectal Cancer Surgery.
机构信息
Department of Surgical Oncology, The University of Tokyo, Tokyo, Japan
Department of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
出版信息
In Vivo. 2022 Jan-Feb;36(1):439-445. doi: 10.21873/invivo.12722.
BACKGROUND/AIM: This study aimed to determine the effectiveness of surgical site infection (SSI) prevention approaches in rectal cancer surgery.
PATIENTS AND METHODS
A total of 1,408 patients who underwent elective rectal cancer surgery between 1995 and 2017 were reviewed. Patients were divided into three groups: control group (group A, n=245), SSI prevention intervention group (group B, n=516), and laparoscopic or robotic surgery group (group C, n=647). The groups were compared in terms of SSI and anastomotic leakage (AL) incidences, and risk factors for SSI were investigated.
RESULTS
The overall SSI and AL rates were 19.4% and 3.6%, respectively. These rates were significantly lower in Group C (9.3%, 1.7%), compared to Groups A (40.0%, 6.1%) and B (22.5%, 3.5%). Abdominoperineal resection, open surgery, operation time, intraoperative bleeding, lack of absorbable sutures, lack of mechanical bowel preparation, and lack of oral antibiotics were independently associated with SSI.
CONCLUSION
SSI reduction after rectal cancer surgery was achieved through various intervention strategies.
背景/目的：本研究旨在确定预防直肠癌手术中手术部位感染（SSI）的方法的有效性。
患者和方法
回顾了 1995 年至 2017 年间接受择期直肠癌手术的 1408 名患者。患者分为三组：对照组（A 组，n=245）、SSI 预防干预组（B 组，n=516）和腹腔镜或机器人手术组（C 组，n=647）。比较了三组 SSI 和吻合口漏（AL）的发生率，并探讨了 SSI 的危险因素。
结果
总的 SSI 和 AL 发生率分别为 19.4%和 3.6%。C 组（9.3%，1.7%）明显低于 A 组（40.0%，6.1%）和 B 组（22.5%，3.5%）。腹会阴联合切除术、开放手术、手术时间、术中出血量、缺乏可吸收缝线、缺乏机械肠道准备以及缺乏口服抗生素与 SSI 独立相关。
结论
通过各种干预策略，直肠癌手术后 SSI 有所减少。
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