Instituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.
Programa de Pós-Graduação em Biologia Parasitária, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Curr Top Microbiol Immunol. 2021;432:1-11. doi: 10.1007/978-3-030-83391-6_1.
So far, extracellular vesicles (EVs) have been described in 15 genera of fungi. They carry molecules that contribute to the interaction of fungal cells with the host. Although the number of studies on fungal EVs has increased, the mechanisms involved in their biogenesis are still poorly understood. The current knowledge of EV biogenesis shows us that they can originate both in the cytoplasm and at the plasma membrane. In this chapter, we will focus on these two cellular sites to review what is known about the biogenesis of fungal EVs.
到目前为止，已经在 15 个真菌属中描述了细胞外囊泡 (EVs)。它们携带的分子有助于真菌细胞与宿主的相互作用。尽管关于真菌 EV 的研究数量有所增加，但它们的生物发生机制仍知之甚少。目前关于 EV 生物发生的知识表明，它们既可以起源于细胞质，也可以起源于质膜。在本章中，我们将重点关注这两个细胞部位，回顾已知的真菌 EV 生物发生情况。
