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Things you wanted to know about fungal extracellular vesicles (but were afraid to ask).

作者信息

Reis Flavia C G, Rodrigues Marcio L

机构信息

Instituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.

Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

出版信息

PLoS Negl Trop Dis. 2025 May 22;19(5):e0013038. doi: 10.1371/journal.pntd.0013038. eCollection 2025 May.

DOI:10.1371/journal.pntd.0013038
PMID:40403031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12097630/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ec/12097630/e9688f16b626/pntd.0013038.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ec/12097630/e9688f16b626/pntd.0013038.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ec/12097630/e9688f16b626/pntd.0013038.g001.jpg

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本文引用的文献

1
Characterizing extracellular vesicles of human fungal pathogens.表征人类真菌病原体的细胞外囊泡。
Nat Microbiol. 2025 Apr;10(4):825-835. doi: 10.1038/s41564-025-01962-4. Epub 2025 Mar 27.
2
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties.肌动蛋白小体是具有细胞样特性的、富含细胞器的大型细胞外囊泡。
Nat Cell Biol. 2025 Mar;27(3):438-448. doi: 10.1038/s41556-025-01621-0. Epub 2025 Feb 21.
3
PMA1-containing extracellular vesicles of triggers immune responses and colitis progression.含PMA1的细胞外囊泡引发免疫反应和结肠炎进展。
Gut Microbes. 2025 Dec;17(1):2455508. doi: 10.1080/19490976.2025.2455508. Epub 2025 Jan 31.
4
Host cell responses to biofilm-derived extracellular vesicles.宿主细胞对生物膜衍生的细胞外囊泡的反应。
Front Cell Infect Microbiol. 2025 Jan 14;14:1499461. doi: 10.3389/fcimb.2024.1499461. eCollection 2024.
5
Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation.来自多种真菌病原体的细胞外囊泡可诱导物种特异性和内吞作用依赖性免疫调节。
bioRxiv. 2025 Jan 3:2025.01.03.631181. doi: 10.1101/2025.01.03.631181.
6
Hidden allies: how extracellular vesicles drive biofilm formation, stress adaptation, and host-immune interactions in human fungal pathogens.隐藏的盟友：细胞外囊泡如何驱动人类真菌病原体中的生物膜形成、应激适应和宿主-免疫相互作用
mBio. 2024 Dec 11;15(12):e0304523. doi: 10.1128/mbio.03045-23. Epub 2024 Nov 18.
7
Toll-like receptor 4 (TLR4) is the major pattern recognition receptor triggering the protective effect of a extracellular vesicle-based vaccine prototype in murine systemic candidiasis.Toll 样受体 4（TLR4）是触发基于细胞外囊泡的疫苗原型在小鼠系统性念珠菌病中发挥保护作用的主要模式识别受体。
mSphere. 2024 Aug 28;9(8):e0046724. doi: 10.1128/msphere.00467-24. Epub 2024 Jul 22.
8
SUR7 deletion in s impacts extracellular vesicle features and delivery of virulence factors.s中的SUR7缺失会影响细胞外囊泡特征和毒力因子的传递。
J Extracell Biol. 2023 May 2;2(5):e82. doi: 10.1002/jex2.82. eCollection 2023 May.
9
Protocol for separation of fungal extracellular vesicles using ultracentrifugation from solid medium cultures.从固体培养基培养物中使用超速离心法分离真菌细胞外囊泡的方案。
STAR Protoc. 2024 Jun 21;5(2):103069. doi: 10.1016/j.xpro.2024.103069. Epub 2024 May 20.
10
Extracellular vesicles from virulent induce TLR4 and dectin-1 expression in innate cells and promote enhanced Th1/Th17 response.毒力株诱导的细胞外囊泡可诱导固有免疫细胞表达 TLR4 和 dectin-1，促进增强的 Th1/Th17 反应。
Virulence. 2024 Dec;15(1):2329573. doi: 10.1080/21505594.2024.2329573. Epub 2024 Mar 21.