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预防性主动引流反流(PARD)在 Ivor-Lewis 食管切除术中的应用,采用负压和双腔开放式多孔膜引流(dOFD)同时进行肠内营养。

Pre-emptive active drainage of reflux (PARD) in Ivor-Lewis oesophagectomy with negative pressure and simultaneous enteral nutrition using a double-lumen open-pore film drain (dOFD).

机构信息

Department for General, Abdominal, Thoracic and Vascular Surgery, Katholisches Marienkrankenhaus Hamburg gGmbH, Alfredstrasse 9, 22087, Hamburg, Germany.

出版信息

Surg Endosc. 2022 Mar;36(3):2208-2216. doi: 10.1007/s00464-021-08933-w. Epub 2022 Jan 1.

Abstract

BACKGROUND

Postoperative reflux can compromise anastomotic healing after Ivor-Lewis oesophagectomy (ILE). We report on Pre-emptive Active Reflux Drainage (PARD) using a new double-lumen open-pore film drain (dOFD) with negative pressure to protect the anastomosis.

METHODS

To prepare a dOFD, the gastric channel of a triluminal tube (Freka®Trelumina, Fresenius) is coated with a double-layered open-pore film (Suprasorb®CNP drainage film, Lohmann & Rauscher) over 25 cm. The ventilation channel is blocked. The filmcoated segment is placed in the stomach and the intestinal feeding tube in the duodenum. Negative pressure is applied with an electronic vacuum pump (- 125 mmHg, continuous suction) to the gastric channel. Depending on the findings in the endoscopic control, PARD will either be continued or terminated.

RESULTS

PARD was used in 24 patients with ILE and started intraoperatively. Healing was observed in all the anastomoses. The median duration of PARD was 8 days (range 4-21). In 10 of 24 patients (40%) there were issues with anastomotic healing which we defined as "at-risk anastomosis". No additional endoscopic procedures or surgical revisions to the anastomoses were required.

CONCLUSIONS

PARD with dOFD contributes to the protection of anastomosis after ILE. Negative pressure applied to the dOFD (a nasogastric tube) enables enteral nutrition to be delivered simultaneously with permanent evacuation and decompression.

摘要

背景

Ivor-Lewis 食管切除术(ILE)后,术后反流可能会影响吻合口愈合。我们报告了使用新的双腔开放式多孔膜引流(dOFD)和负压来预防反流的前瞻性主动反流引流(PARD),以保护吻合口。

方法

为了制备 dOFD,将三腔管(Freka®Trelumina,Fresenius)的胃腔用双层开放式多孔膜(Suprasorb®CNP 引流膜,Lohmann & Rauscher)覆盖 25cm 以上。通风通道被阻塞。将覆膜段置于胃中,肠内喂养管置于十二指肠中。用电子真空泵(-125mmHg,持续抽吸)对胃腔施加负压。根据内镜检查结果,继续或终止 PARD。

结果

24 例 ILE 患者术中开始使用 PARD,所有吻合口均愈合。PARD 的中位持续时间为 8 天(范围 4-21)。在 24 例患者中的 10 例(40%)存在吻合口愈合问题,我们将其定义为“有风险的吻合口”。不需要额外的内镜治疗或手术修复吻合口。

结论

dOFD 的 PARD 有助于保护 ILE 后的吻合口。dOFD(鼻胃管)施加的负压可同时进行肠内营养输送和永久性引流和减压。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a4/8847238/3f189c49f84d/464_2021_8933_Fig1_HTML.jpg

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