Mohr R, Lavee J, Goor D A
J Thorac Cardiovasc Surg. 1987 Aug;94(2):286-90.
The phenomenon of a pressure gradient between central and radial arteries was evaluated in 48 patients immediately after coronary artery bypass operations. All were in stable hemodynamic condition, none receiving catecholamine support. In eight patients (Group A) mean femoral pressure was significantly higher than mean radial pressure (range 10 to 30 mm Hg). In the remaining 40 (Group B) radial and femoral pressures were equal. Mean cardiac index (thermodilution) was 3.3 +/- 0.68 versus 2.1 +/- 0.4 L/min/m2, systemic vascular resistance 1,181 +/- 218.4 versus 2,049 +/- 501 dynes/sec/cm-5, toe temperature 23.8 degrees +/- 1.2 degrees C versus 24.02 degrees +/- 0.9 degrees C, core temperature 33.9 degrees +/- 0.5 degrees C versus 34.1 degrees +/- 0.6 degrees C, mixed venous oxygen saturation 78% +/- 3% versus 62% +/- 5%, and peak radial dP/dt 1,485 +/- 366 versus 2,028 +/- 392 in Groups A and B, respectively. These data indicate, first, that the low radial pressures measured in Group A patients did not represent the true central aortic pressures; that is, they were false. Second, these low pressures had nothing to do with compromised cardiac function; rather, they were due to peripheral constriction and volume factors and also probably to proximal shunting. It is therefore recommended that while the chest is still open, if a discrepancy exists between a low radial artery pressure, a high palpable aortic pressure, and a satisfactory cardiac contraction, a femoral cannula for pressure measurement should be inserted. Treatment is by blood infusion until the femoral-radial gradient has been abolished.
在48例冠状动脉搭桥手术后的患者中,立即评估了中央动脉和桡动脉之间的压力梯度现象。所有患者血流动力学状况稳定,均未接受儿茶酚胺支持。8例患者(A组)股动脉平均压显著高于桡动脉平均压(范围为10至30 mmHg)。其余40例(B组)桡动脉压和股动脉压相等。A组和B组的平均心脏指数(热稀释法)分别为3.3±0.68与2.1±0.4 L/min/m²,全身血管阻力为1181±218.4与2049±501 dynes/sec/cm⁻⁵,趾端温度为23.8℃±1.2℃与24.02℃±0.9℃,核心温度为33.9℃±0.5℃与34.1℃±0.6℃,混合静脉血氧饱和度为78%±3%与62%±5%,桡动脉峰值dP/dt分别为1485±366与2028±392。这些数据表明,首先,A组患者测得的低桡动脉压并不代表真正的中心主动脉压;也就是说,这些是假的。其次,这些低压与心功能受损无关;相反,它们是由于外周血管收缩和容量因素,也可能是由于近端分流所致。因此建议,在胸部仍开放时,如果桡动脉压低、可触及的主动脉压高且心脏收缩良好之间存在差异,应插入股动脉插管进行压力测量。治疗方法是输血,直到股动脉-桡动脉梯度消除。