Department of Surgery, Division of Oral and Maxillofacial Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 Jun;133(6):639-642. doi: 10.1016/j.oooo.2021.11.002. Epub 2021 Nov 12.
The purpose of this study was to determine whether various serum marker levels (C-reactive protein [CRP], white blood cell [WBC] count, glucose) or body temperature at admission are associated with severity of odontogenic infections.
This retrospective chart review of patients admitted to the hospital for treatment of severe odontogenic infections (SOIs) over a 5-year period (2016-2020) assigned patients with a severity score (SS) ≥5 to group A and those with an SS <5 to group B. Serum marker levels and temperature at admission were collected, and comparisons between group A and group B were conducted for serum marker levels and body temperature at admission using 2-sample t tests.
The mean serum CRP and temperature at admission between the 2 groups was not statistically significant (P > .05). The mean WBC count and serum glucose at admission between the 2 groups was statistically significant (P = .001 and P = .036, respectively).
This study demonstrates that serum glucose and WBC at admission are significantly higher in patients with more SOIs. In addition, serum CRP and body temperature at admission are not adequate prognostic indicators of odontogenic infection severity.
本研究旨在确定入院时各种血清标志物水平(C 反应蛋白[CRP]、白细胞[WBC]计数、血糖)或体温是否与牙源性感染的严重程度相关。
本研究回顾性分析了 5 年来(2016-2020 年)因严重牙源性感染(SOI)入院治疗的患者的病历,将严重程度评分(SS)≥5 的患者分为 A 组,SS<5 的患者分为 B 组。收集入院时的血清标志物水平和体温,并使用两样本 t 检验比较 A 组和 B 组入院时的血清标志物水平和体温。
两组间入院时的平均血清 CRP 和体温无统计学意义(P>.05)。两组间入院时的平均 WBC 计数和血清葡萄糖有统计学意义(P=.001 和 P=.036)。
本研究表明,入院时血清葡萄糖和 WBC 计数在 SOI 较多的患者中显著升高。此外,入院时血清 CRP 和体温不是牙源性感染严重程度的充分预后指标。