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[阴道毛滴虫、口腔毛滴虫和人毛滴虫总水溶性提取物的比较免疫电泳研究]

[Comparative immunoelectrophoretic studies of total water-soluble extracts of Trichomonas vaginalis, T. tenax and T. hominis].

作者信息

Cvetkova A, Komandarev S, Mihov L, Andreeva N, Isev V

出版信息

Angew Parasitol. 1987 May;28(2):69-72.

PMID:3497593
Abstract

An antigen characterization was carried out by the method of two-dimensional immunoelectrophoresis, and on this basis the antigen community and the antigenic differences between the 3 Trichomonas species parasitic in man were investigated. In the homologous antigen-antibody-systems a maximum number of precipitation curves is formed--21 in T. vaginalis and 20 each in T. tenax and T. hominis. According to our setting of the experiment T. vaginalis has 5 specific antigens in regard to T. tenax and 3 in regard to T. hominis. T. tenax has 2 specific antigens in regard to T. vaginalis and 7 in regard to T. hominis, T. hominis has 2 specific antigens in regard to T. vaginalis and 3 in regard to T. tenax. The presence of antigenic differences is important for the immunological characterization of the 3 species and demonstrates their validity.

摘要

采用二维免疫电泳法进行抗原特性分析,并在此基础上研究了寄生于人体的3种毛滴虫的抗原群落及抗原差异。在同源抗原-抗体系统中形成了最大数量的沉淀曲线——阴道毛滴虫中有21条,口腔毛滴虫和人毛滴虫中各有20条。根据我们的实验设置,阴道毛滴虫相对于口腔毛滴虫有5种特异性抗原,相对于人毛滴虫有3种特异性抗原。口腔毛滴虫相对于阴道毛滴虫有2种特异性抗原,相对于人毛滴虫有7种特异性抗原,人毛滴虫相对于阴道毛滴虫有2种特异性抗原,相对于口腔毛滴虫有3种特异性抗原。抗原差异的存在对于这3种毛滴虫的免疫学特性分析很重要,并证明了它们的有效性。

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