Kim SoJung, Singh Harshvardhan
Department of Health and Exercise Science, School of Nursing & Health Professions, Rowan University, Glassboro, NJ, 08028, USA.
Department of Physical Therapy, University of Alabama, 1716 9th Avenue South, Birmingham, AL, 35294, USA.
J Exerc Sci Fit. 2022 Jan;20(1):27-31. doi: 10.1016/j.jesf.2021.12.002. Epub 2021 Dec 8.
BACKGROUND/OBJECTIVE: Physical inactivity is one of the major cardiovascular disease risk factors; however, not much is known regarding lifetime bone-specific physical activity and arterial stiffness. The aim of this cross-sectional study was to determine whether total bone-specific physical activity score (tBPAQ) was related to arterial stiffness and body composition in healthy young adults.
Healthy young women (n = 56, 20.3 ± 1.3 years) and men (n = 52, 21.0 ± 1.2 years) between 18 and 25 years were recruited for this study. The tBPAQ was used to obtain a comprehensive account of lifetime bone-loading physical activity. We measured the carotid to femoral pulse wave velocity (cfPWV) to evaluate arterial stiffness using the novel oscillometric device (SphygmoCor XCEL). Dual energy X-ray absorptiometry was used to measure bone free lean body mass (BFLBM, kg) and % total body fat.
Partial correlations analyses showed a significant inverse relationship between tBPAQ and cfPWV (r = - 0.371, p = 0.007) in young women; however, this relationship was not found in young men (p > 0.05). There were significant negative correlations between tBPAQ and % total body fat in both young women (r = - 0.265, p = 0.048) and men (r = - 0.327, p = 0.018). No significant relationships were found between tBPAQ and BFLBM (p > 0.05).
Our study provides preliminary evidence of sex-specificity of negative relationships of tBPAQ with i) cfPWV (women only) and ii) % total body fat (men and women). Whether bone-loading physical activity can lead to better cardiometabolic outcomes needs to be examined.
背景/目的：缺乏身体活动是主要的心血管疾病风险因素之一；然而，关于一生当中特定于骨骼的身体活动与动脉僵硬度之间的关系，我们了解得并不多。这项横断面研究的目的是确定总的特定于骨骼的身体活动评分（tBPAQ）是否与健康年轻成年人的动脉僵硬度和身体成分有关。
本研究招募了年龄在18至25岁之间的健康年轻女性（n = 56，20.3±1.3岁）和男性（n = 52，21.0±1.2岁）。tBPAQ用于全面了解一生当中的骨骼负荷身体活动情况。我们使用新型示波装置（SphygmoCor XCEL）测量颈股脉搏波速度（cfPWV）以评估动脉僵硬度。采用双能X线吸收法测量去骨瘦体重（BFLBM，千克）和全身脂肪百分比。
偏相关分析显示，年轻女性的tBPAQ与cfPWV之间存在显著负相关（r = -0.371，p = 0.007）；然而，在年轻男性中未发现这种关系（p>0.05）。年轻女性（r = -0.265，p = 0.048）和男性（r = -0.327，p = 0.018）的tBPAQ与全身脂肪百分比之间均存在显著负相关。未发现tBPAQ与BFLBM之间存在显著关系（p>0.05）。
我们的研究提供了初步证据，证明tBPAQ与以下因素之间的负相关存在性别特异性：i）cfPWV（仅女性）和ii）全身脂肪百分比（男性和女性）。骨骼负荷身体活动是否能带来更好的心脏代谢结果有待进一步研究。
