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青春期前儿童客观测量的身体活动和久坐时间与动脉僵硬度的关联。

Associations of Objectively Measured Physical Activity and Sedentary Time With Arterial Stiffness in Pre-Pubertal Children.

作者信息

Haapala Eero A, Väistö Juuso, Veijalainen Aapo, Lintu Niina, Wiklund Petri, Westgate Kate, Ekelund Ulf, Lindi Virpi, Brage Soren, Lakka Timo A

机构信息

1 University of Eastern Finland.

2 University of Jyväskylä.

出版信息

Pediatr Exerc Sci. 2017 Aug;29(3):326-335. doi: 10.1123/pes.2016-0168. Epub 2017 Jan 25.

Abstract

PURPOSE

To investigate the relationships of objectively measured physical activity (PA) and sedentary time (ST) to arterial stiffness in prepubertal children.

METHOD

Altogether 136 children (57 boys, 79 girls) aged 6-8-years participated in the study. Stiffness index (SI) was assessed by pulse contour analysis based on photoplethysmography. ST, light PA, moderate PA, and vigorous PA were assessed using combined acceleration and heart rate monitoring. We investigated the associations of ST (<1.5METs) and time spent in intensity level of PA above 2-7METs in min/d with SI using linear regression analysis. We studied the optimal duration and intensity of PA to identify children being in the highest quarter of SI using Receiver Operating Characteristics curves.

RESULTS

Moderate PA, vigorous PA, and cumulative time spent in PA above 3 (β=-0.279, p = .002), 4 (β =-0.341, P<0.001), 5 (β =-0.349, P<0.001), 6 (β =-0.312, P<0.001), and 7 (β =-0.254, p = .005) METs were inversely associated with SI after adjustment for age, sex, and monitor wear time. The cutoffs for identifying children being in the highest quarter of SI <68 min/d for PA exceeding 5 METs and <26 min/d for PA exceeding 6 METs.

CONCLUSION

Lower levels of PA exceeding 3-6 METs were related to higher arterial stiffness in children.

摘要

目的

探讨青春期前儿童客观测量的身体活动(PA)和久坐时间(ST)与动脉僵硬度之间的关系。

方法

共有136名6至8岁的儿童(57名男孩,79名女孩)参与了该研究。基于光电容积脉搏波描记法通过脉搏轮廓分析评估僵硬度指数(SI)。使用加速度和心率监测相结合的方法评估ST、轻度PA、中度PA和剧烈PA。我们使用线性回归分析研究了ST(<1.5代谢当量)以及每天以分钟为单位的PA强度水平超过2 - 7代谢当量的时间与SI之间的关联。我们使用受试者工作特征曲线研究PA的最佳持续时间和强度,以识别处于SI最高四分位数的儿童。

结果

在对年龄、性别和监测佩戴时间进行调整后,中度PA、剧烈PA以及PA强度超过3(β = -0.279,p = 0.002)、4(β = -0.341,P < 0.001)、5(β = -0.349,P < 0.001)、6(β = -0.312,P < 0.001)和7(β = -0.254,p = 0.005)代谢当量的累积时间与SI呈负相关。识别处于SI最高四分位数儿童的临界值为:PA超过5代谢当量时<68分钟/天,PA超过6代谢当量时<26分钟/天。

结论

PA强度超过3 - 6代谢当量的较低水平与儿童较高的动脉僵硬度相关。

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