Shafiezadeh Neda, Ibrahimi Reza, Mozdourian Mahnaz
Department of Internal Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Lung Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran.
Tanaffos. 2021 Feb;20(2):180-183.
Looking at the recent data provided in literature, we can see an association between cardiovascular and cerebrovascular accidents in COVID-19 thought to be related to severe inflammation and prothrombotic environment caused by the virus. This article reports a patient presenting with typical signs and symptoms of SARS-CoV-2 infection including flu like symptoms and respiratory distress. Initially a chest CT was performed that showed characteristic findings of atypical pneumonia caused by SARS-CoV-2 virus which was later confirmed with a nasopharyngeal PCR positive for COVID-19. During the course of admission patient developed unstable angina. Further testing confirmed an acute ST elevation myocardial infarction. While on anticoagulant treatment, patient showed signs of cerebrovascular accident. An emergency brain CT was ordered which did not yield any significant changes supporting our clinical diagnosis. Further diagnostic workup using magnetic resonance imaging disclosed evidence of cerebral ischemia in medial cerebral artery territory. Our study suggests that prophylactic anticoagulant regiment is not reassuring in COVID-19 patients and close observation and vigilance, can help clinicians to act timely and can improve patient survival.
查看文献中最近提供的数据,我们可以看到在COVID-19中,心血管和脑血管意外之间存在关联,这被认为与病毒引起的严重炎症和促血栓形成环境有关。本文报告了一名出现SARS-CoV-2感染典型体征和症状的患者,包括流感样症状和呼吸窘迫。最初进行了胸部CT检查,显示出由SARS-CoV-2病毒引起的非典型肺炎的特征性表现,后来通过鼻咽PCR检测确诊为COVID-19阳性。在住院期间,患者出现了不稳定型心绞痛。进一步检查确诊为急性ST段抬高型心肌梗死。在接受抗凝治疗期间,患者出现了脑血管意外的迹象。于是进行了紧急脑部CT检查,但未发现任何支持我们临床诊断的显著变化。使用磁共振成像进行的进一步诊断检查发现大脑中动脉区域存在脑缺血的证据。我们的研究表明,预防性抗凝方案对COVID-19患者并不令人放心,密切观察和警惕可以帮助临床医生及时采取行动,并提高患者生存率。