Doménech-Carbó María Teresa, Doménech-Carbó Antonio
Institut de Restauració del Patrimoni, Universitat Politècnica de València, Camí de Vera 14, 46022 Valencia, Spain.
Departament de Química Analítica, Universitat de València. Dr. Moliner, 50, Burjassot, 46100 Valencia, Spain.
ChemTexts. 2022;8(1):4. doi: 10.1007/s40828-021-00152-z. Epub 2021 Dec 27.
Microchemistry, i.e., the chemistry performed at the scale of a microgram or less, has its roots in the late eighteenth and early nineteenth centuries. In the first half of the twentieth century a wide range of spot tests have been developed. For didactic reasons, they are still part of the curriculum of chemistry students. However, they are even highly important for applied analyses in conservation of cultural heritage, food science, forensic science, clinical and pharmacological sciences, geochemistry, and environmental sciences. Modern pregnancy tests, virus tests, etc. are the most recent examples of sophisticated spot tests. The present contribution aims to provide an overview of the past and present of this analytical methodology.
微量化学，即规模在微克或更低水平上进行的化学，其根源可追溯到18世纪末和19世纪初。在20世纪上半叶，人们开发了各种各样的点滴试验。出于教学目的，它们仍然是化学专业学生课程的一部分。然而，它们对于文化遗产保护、食品科学、法医学、临床和药理科学、地球化学以及环境科学等领域的应用分析而言甚至极为重要。现代妊娠试验、病毒检测等就是复杂点滴试验的最新例子。本文旨在概述这种分析方法的过去和现在。
