Chen Hailiu, Meng Jie, Lu Peng, Ye Dan, Li Yunxuan, Cheng Lu, Li Yangyunhui, Liang Xiaoling, Huang Wenyong, Huang Jingjing
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Department of Ophthalmology, Joint Shantou International Eye Center, Shantou University, Chinese University of Hong Kong, Shantou, China.
Front Med (Lausanne). 2021 Dec 17;8:761550. doi: 10.3389/fmed.2021.761550. eCollection 2021.
To investigate the error rate of segmentation in the automatic measurement of anterior chamber volume (ACV) and iris volume (IV) by swept-source anterior segment optical coherence tomography (SS-ASOCT) in narrow-angle and wide-angle eyes. In this study, fifty eyes from 25 narrow-angle subjects and fifty eyes from 25 wide-angle subjects were enrolled. SS-ASOCT examinations were performed and each SS-ASOCT scan was reviewed, and segmentation errors in the automatic measurement of ACV and IV were classified and manually corrected. Error rates were compared between the narrow-angle and the wide-angle groups, and ACV and IV before and after manual correction were compared. A total of 12,800 SS-ASOCT scans were reviewed. Segmentation error rates of angle recess, iris root, posterior surface of the iris, pupil margin, and anterior surface of the lens were 84.06, 93.30, 13.15, 59.21, and 25.27%, respectively. Segmentation errors of angle recess, iris root, posterior surface of the iris, and pupil margin occurred more frequently in narrow-angle eyes, while more segmentation errors of the anterior surface of the lens were found in wide-angle eyes (all < 0.001). ACV decreased and IV increased significantly after manual correction of segmentation errors in both groups (all < 0.01). Segmentation errors were prevalent in the volumetric measurement by SS-ASOCT, particularly in narrow-angle eyes, leading to mismeasurement of ACV and IV.
探讨扫频源眼前节光学相干断层扫描（SS-ASOCT）自动测量窄角眼和广角眼前房容积（ACV）及虹膜容积（IV）时的分割错误率。本研究纳入了25例窄角受试者的50只眼和25例广角受试者的50只眼。进行了SS-ASOCT检查，并对每次SS-ASOCT扫描进行回顾，对ACV和IV自动测量中的分割错误进行分类并手动校正。比较窄角组和广角组之间的错误率，并比较手动校正前后的ACV和IV。共回顾了12,800次SS-ASOCT扫描。房角隐窝、虹膜根部、虹膜后表面、瞳孔边缘和晶状体前表面的分割错误率分别为84.06%、93.30%、13.15%、59.21%和25.27%。房角隐窝、虹膜根部、虹膜后表面和瞳孔边缘的分割错误在窄角眼中更常见，而广角眼中晶状体前表面的分割错误更多（均P<0.001）。两组手动校正分割错误后，ACV显著降低，IV显著增加（均P<0.01）。SS-ASOCT容积测量中分割错误普遍存在，尤其是在窄角眼中，导致ACV和IV测量错误。
