Falavarjani Khalil Ghasemi, Mehrpuya Amirabbas, Amirkourjani Foad
a Department of Ophthalmology, Eye Research Center , Rassoul Akram Hospital, Iran University of Medical Sciences , Tehran , Iran.
b Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences , Tehran , Iran.
Curr Eye Res. 2017 Feb;42(2):282-286. doi: 10.1080/02713683.2016.1179332. Epub 2016 Jun 30.
To evaluate the effect of Topcon spectral domain optical coherence tomography (OCT) image quality on macular thickness measurements and the error rate in healthy subjects and patients with clinically significant diabetic macular edema (CSME).
In this prospective, comparative case series, macular thickness measurements, and the rate of decentration and segmentation errors were evaluated before and after reducing the image quality factor (QF). The measurements were evaluated again after correcting the decentration and segmentation errors. To reduce the image QF below 45, tetracycline eye ointment was applied on the corneal surface.
Forty eyes of 40 subjects including 18 healthy eyes and 22 eyes with CSME were included. In both groups, the difference in central subfield thickness measurements before and after reducing the image QF was not statistically significant both before and after error correction (all P>0.05). The rate of decentration error was statistically similar before and after reducing image QF in normal and CSME eyes (P=0.50, P=0.69, respectively). However, the rate of segmentation error was statistically significantly higher after reducing image QF both in normal and CSME eyes (P=0.008 and P=0.004, respectively). In both groups, eyes with a segmentation error had higher image QF reduction (both P=0.01).
Reducing image quality results in a higher rate of the segmentation error in normal eyes and in eyes with CSME.
评估拓普康光谱域光学相干断层扫描（OCT）图像质量对黄斑厚度测量的影响以及在健康受试者和患有临床显著性糖尿病黄斑水肿（CSME）患者中的误差率。
在这个前瞻性、对比性病例系列研究中，在降低图像质量因子（QF）前后评估黄斑厚度测量、偏心率和分割误差率。在纠正偏心和分割误差后再次评估测量结果。为了将图像QF降低到45以下，在角膜表面涂抹四环素眼膏。
纳入了40名受试者的40只眼睛，包括18只健康眼睛和22只患有CSME的眼睛。在两组中，降低图像QF前后中央子区域厚度测量的差异在误差校正前后均无统计学意义（所有P>0.05）。正常眼睛和CSME眼睛在降低图像QF前后偏心误差率在统计学上相似（分别为P=0.50，P=0.69）。然而，在正常眼睛和CSME眼睛中，降低图像QF后分割误差率在统计学上均显著更高（分别为P=0.008和P=0.004）。在两组中，存在分割误差的眼睛图像QF降低幅度更大（均为P=0.01）。
降低图像质量会导致正常眼睛和患有CSME的眼睛中分割误差率更高。
