来自意大利中部的100名1型（胰岛素依赖型）糖尿病患者的HLA分型数据显示，与DR5呈负相关，而非与DR2呈负相关。
HLA typing data on 100 type 1 (insulin-dependent) diabetic patients from central Italy show a negative association with DR5 rather than with DR2.
作者信息
Vela M, Adorno D, Longo A, Papola F, Maccarone D, Centis D, Raponi M P, Candela A, Campea L, Orsini M
出版信息
Clin Immunol Immunopathol. 1987 Oct;45(1):143-6. doi: 10.1016/0090-1229(87)90121-8.
PMID:3497749
Abstract
HLA typing of 100 Type 1 diabetic patients from the Rome area confirmed the strong association with DR3 and DR4 and the prevalence of DR3/4 heterozygotes. However, DR5 rather than DR2 showed a significantly negative association.
摘要
对来自罗马地区的100名1型糖尿病患者进行的HLA分型证实了其与DR3和DR4的强关联以及DR3/4杂合子的患病率。然而，与DR2相比，DR5显示出显著的负相关。
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