Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Department of Urology, Laohekou No.1 People's Hospital, Laohekou 441800, China.
Urol J. 2022 Jan 3;19(1):83-88. doi: 10.22037/uj.v18i.6856.
Bipolar transurethral resection of the prostate (TURP) is an effective and safe alternative to monopolar TURP. The aim of this study was to investigate the influence of resected prostate weight on the clinical outcome improvement after bipolar TURP for benign prostatic hyperplasia (BPH) patients.
A total of 233 men with BPH who underwent bipolar TURP were included in this prospective study. International Prostate Symptom Score (I-PSS), quality of life (QoL), maximum flow rate (Qmax) and post-void residual urine volume (PVR) were assessed preoperatively and 3 months postoperatively. The relationship between the resected prostatic weight ratio (RPWR, %) and clinical improvement was investigated.
Significant improvements in Qmax, PVR, I-PSS and QoL were found 3 months after operation, and Qmax was correlated with RPWR (r = 0.1521, P = .020). The RPWR was significantly higher in patients with postoperative Qmax > 20 mL/s (P = .049). Moreover, Qmax at 3-month follow-up was higher in patients with RPWR over 50% than patients with RPWR between 0-25% (P < .05). In addition, patients with larger prostate volume tended to gain better Qmax and I-PSS postoperatively (P < .05).
The RPWR exerts an influence on postoperative Qmax, rather than I-PSS and QoL score, and patients with larger prostate volume tend to gain better clinical outcomes from bipolar TURP than those who with smaller prostates.
双极经尿道前列腺切除术(TURP)是治疗良性前列腺增生(BPH)的有效且安全的方法,可作为传统单极 TURP 的替代方法。本研究旨在探讨前列腺切除量对双极 TURP 治疗 BPH 患者临床疗效的影响。
前瞻性研究纳入 233 例行双极 TURP 的 BPH 患者。术前和术后 3 个月评估国际前列腺症状评分(I-PSS)、生活质量评分(QoL)、最大尿流率(Qmax)和剩余尿量(PVR)。分析前列腺切除量与临床改善的关系。
术后 3 个月,Qmax、PVR、I-PSS 和 QoL 均显著改善,Qmax 与 RPWR 呈正相关(r = 0.1521,P =.020)。术后 Qmax>20ml/s 的患者 RPWR 明显更高(P =.049)。此外,RPWR>50%的患者在 3 个月随访时的 Qmax 高于 RPWR 在 0-25%的患者(P<.05)。此外,前列腺体积较大的患者术后 Qmax 和 I-PSS 改善更明显(P<.05)。
RPWR 对术后 Qmax 有影响,而对 I-PSS 和 QoL 评分无影响,且前列腺体积较大的患者行双极 TURP 治疗后的临床获益优于前列腺体积较小的患者。