Sussman Morgan, Zhai Lisa, Morquette Alexandra, Huang Simo, Hsu Sylvia
Department of Dermatology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.
Department of Dermatology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.
Clin Dermatol. 2022 Sep-Oct;40(5):516-528. doi: 10.1016/j.clindermatol.2021.12.012. Epub 2022 Jan 1.
Annular bullous dermatoses represent an etiologically diverse group of cutaneous phenomena that present with a figurate morphology in association with vesicles and bullae. This group of diverse conditions consists of bullous pemphigoid; pemphigoid gestationis; epidermolysis bullosa simplex, Dowling-Meara type; linear immunoglobulin A bullous dermatosis; chronic bullous disease of childhood; anti-p200 pemphigoid; subcorneal pustular dermatosis; and immunoglobulin A pemphigus. Astute examination of clinical, histopathologic, and serologic features is crucial in distinguishing these bullous dermatoses. We review the clinical presentation, pathophysiology, histopathology, and treatments for each bullous annular disease to aid physicians in their recognition, diagnosis, and management.
环状大疱性皮肤病是一组病因多样的皮肤现象,表现为具有图形形态并伴有水疱和大疱。这组不同的病症包括大疱性类天疱疮、妊娠类天疱疮、单纯性大疱性表皮松解症(Dowling-Meara型)、线状免疫球蛋白A大疱性皮肤病、儿童慢性大疱性疾病、抗p200类天疱疮、角层下脓疱性皮肤病和免疫球蛋白A天疱疮。对临床、组织病理学和血清学特征进行敏锐检查对于区分这些大疱性皮肤病至关重要。我们回顾了每种环状大疱性疾病的临床表现、病理生理学、组织病理学和治疗方法,以帮助医生进行识别、诊断和管理。