Ophthalmic Surg Lasers Imaging Retina. 2022 Jan;53(1):12-21. doi: 10.3928/23258160-20211213-01. Epub 2022 Jan 1.
No consensus exists on the comparative efficacy and safety of sutured scleral-fixated (SSF) and anterior chamber (AC) intraocular lens (IOL) implantation. We aim to compare outcomes of these two techniques.
A systematic literature search of MEDLINE, Embase, and Cochrane CENTRAL was conducted (2005 to 2020). Studies comparing SSFIOLs with ACIOLs were included. Outcomes included corrected distance visual acuity and complications. A meta-analysis was conducted with a random effects model. Weighted mean differences and risk ratios with 95% CIs were computed.
Seven hundred eighty-three eyes from nine studies were included. SSFIOLs had a significantly higher absolute postoperative spherical equivalent (weighted mean difference, 0.32; 95% CI, 0.03 to 0.60; = .03; low certainty) and incidence of IOL decentration/subluxation (risk ratio, 2.69; 95% CI, 1.03 to 7.01; = .04; moderate certainty) than ACIOLs. There was no difference in final corrected distance visual acuity ( = .26).
SSFIOLs have a higher absolute postoperative spherical equivalent and incidence of IOL decentration/subluxation than ACIOLs. Future prospective studies are needed to confirm these findings. .
在缝合性巩膜固定（SSF）和前房（AC）人工晶状体（IOL）植入的比较疗效和安全性方面，尚无共识。我们旨在比较这两种技术的结果。
对 MEDLINE、Embase 和 Cochrane CENTRAL 进行了系统的文献检索（2005 年至 2020 年）。纳入比较 SSFIOL 与 ACIOL 的研究。结局包括矫正远距视力和并发症。采用随机效应模型进行荟萃分析。计算加权均数差和 95%CI 的风险比。
来自 9 项研究的 783 只眼被纳入。SSFIOL 的术后绝对球镜等效（加权均数差，0.32；95%CI，0.03 至 0.60； =.03；低确定性）和 IOL 偏位/半脱位的发生率（风险比，2.69；95%CI，1.03 至 7.01； =.04；中等确定性）显著高于 ACIOL。最终矫正远距视力无差异（ =.26）。
SSFIOL 的术后绝对球镜等效和 IOL 偏位/半脱位发生率高于 ACIOL。需要前瞻性研究来证实这些发现。
