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带盖的 3D 打印拭子,用于精准诊断。

3D-printed swab with cover for precision diagnosis.

机构信息

Department of Modern Mechanical Engineering, Waseda University, Tokyo, Japan.

Department of Anesthesiology and Pain Relief Center, The University of Tokyo Hospital, Tokyo, Japan.

出版信息

J Mater Sci Mater Med. 2022 Jan 4;33(1):8. doi: 10.1007/s10856-021-06635-2.

DOI:10.1007/s10856-021-06635-2
PMID:34982267
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8724228/
Abstract

The collection capacity of common nasopharyngeal swabs and irregularities of medical personnel limit the accuracy of PCR testing. This study describes a newly designed 3D-printed swab that is combined with a 3D-printed cover to prevent the extraction of undesired nasal secretions. This swab improved the accuracy of PCR test results. The results of a series of experiments showed that, because of the mucus extraction effect, 3D-printed swabs can replace ordinary cotton swabs. The crisis of the worldwide medical supply shortage can be ameliorated to a certain extent by applying 3D printing technology.

摘要

普通鼻咽拭子的采集能力和医务人员的不规范操作限制了 PCR 检测的准确性。本研究描述了一种新设计的 3D 打印拭子,它与 3D 打印盖结合在一起,以防止提取不需要的鼻腔分泌物。这种拭子提高了 PCR 检测结果的准确性。一系列实验结果表明,由于粘液提取效果,3D 打印拭子可以替代普通棉签。通过应用 3D 打印技术,可以在一定程度上缓解全球医疗用品短缺的危机。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/c8986f7e023c/10856_2021_6635_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/19b1285cb7d2/10856_2021_6635_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/f92f648e1498/10856_2021_6635_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/ca675faac56c/10856_2021_6635_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/d4e78f01ed18/10856_2021_6635_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/5e100318658f/10856_2021_6635_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/611e543f4f1c/10856_2021_6635_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/543cff98ab29/10856_2021_6635_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/385e57a85b1a/10856_2021_6635_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/c8986f7e023c/10856_2021_6635_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/19b1285cb7d2/10856_2021_6635_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/f92f648e1498/10856_2021_6635_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/8b49c2312fde/10856_2021_6635_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/ca675faac56c/10856_2021_6635_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/d4e78f01ed18/10856_2021_6635_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/5e100318658f/10856_2021_6635_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/611e543f4f1c/10856_2021_6635_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/543cff98ab29/10856_2021_6635_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/385e57a85b1a/10856_2021_6635_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b47a/8727418/c8986f7e023c/10856_2021_6635_Fig10_HTML.jpg

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本文引用的文献

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Estimating the false-negative test probability of SARS-CoV-2 by RT-PCR.估算 RT-PCR 检测 SARS-CoV-2 的假阴性率。
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Prospective clinical validation of 3D printed nasopharyngeal swabs for diagnosis of COVID-19.前瞻性临床验证 3D 打印鼻咽拭子用于 COVID-19 诊断。
Diagn Microbiol Infect Dis. 2021 Mar;99(3):115257. doi: 10.1016/j.diagmicrobio.2020.115257. Epub 2020 Oct 22.
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3D printed auxetic nasopharyngeal swabs for COVID-19 sample collection.
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J Mech Behav Biomed Mater. 2021 Feb;114:104175. doi: 10.1016/j.jmbbm.2020.104175. Epub 2020 Nov 12.
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