Shaw P J, Bates D, Cartlidge N E, Heaviside D, French J M, Julian D G, Shaw D A
Acta Neurol Scand. 1987 Jul;76(1):1-7. doi: 10.1111/j.1600-0404.1987.tb03535.x.
In a prospective study of neurological complications of coronary bypass surgery, detailed pre- and post-operative bedside ophthalmological evaluation was undertaken in 312 patients. Post-operative neuro-ophthalmological complications developed in 80/312 (25.6%) patients and included: areas of retinal infarction (17.3%); retinal emboli (2.6%); visual field defects (2.6%); reduction of visual acuity (4.5%) and Horner's syndrome (1.3%). Neuro-ophthalmological complications were not observed in a control group of 50 patients undergoing major peripheral vascular surgery. Ten of 75 patients reviewed at 6 months still had detectable neuro-ophthalmological abnormalities, but functional disability occurred only in those with persistent visual field defects. Multivariate analysis revealed that extra-coronary vascular disease, severe and prolonged duration of heart disease prior to operation, and large drop in haemoglobin level during surgery may predispose to neuro-ophthalmological complications.
在一项关于冠状动脉搭桥手术神经并发症的前瞻性研究中，对312例患者进行了详细的术前和术后床边眼科评估。80/312（25.6%）例患者出现术后神经眼科并发症，包括：视网膜梗死区域（17.3%）；视网膜栓子（2.6%）；视野缺损（2.6%）；视力下降（4.5%）和霍纳综合征（1.3%）。在50例接受外周大血管手术的患者组成的对照组中未观察到神经眼科并发症。在6个月时复查的75例患者中有10例仍有可检测到的神经眼科异常，但只有那些有持续性视野缺损的患者出现功能残疾。多变量分析显示，冠状动脉外血管疾病、术前严重且病程长的心脏病以及手术期间血红蛋白水平大幅下降可能易导致神经眼科并发症。
