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一例冠状动脉搭桥术体外循环后双侧视网膜梗死的病例报告及文献简要回顾

A case report and brief review of the literature on bilateral retinal infarction following cardiopulmonary bypass for coronary artery bypass grafting.

作者信息

Trethowan Brian A, Gilliland Helen, Popov Aron F, Varadarajan Barathi, Phillips Sally-Anne, McWhirter Louise, Ghent Robert

机构信息

Department of Anaesthesia, Royal Group of Hospitals and Dental Hospital Health and Social Services Trust, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland.

出版信息

J Cardiothorac Surg. 2011 Nov 21;6:154. doi: 10.1186/1749-8090-6-154.

Abstract

Postoperative visual loss is a devastating perioperative complication. The commonest aetiologies are anterior ischaemic optic neuropathy (AION), posterior ischaemic optic neuropathy (PION), and central retinal artery occlusion (CRAO). These appear to be related to certain types of operation, most commonly spinal and cardiac bypass procedures; with the rest divided between: major trauma causing excessive blood loss; head/neck and nasal or sinus surgery; major vascular procedures (aortic aneurysm repair, aorto-bifemoral bypass); general surgery; urology; gynaecology; liposuction; liver transplantation and duration of surgery. The non-surgical risk factors are multifactorial: advanced age, prolonged postoperative anaemia, positioning (supine v prone), alteration of venous drainage of the retina, hypertension, smoking, atherosclerosis, hyperlipidaemia, diabetes, hypercoagulability, hypotension, blood loss and large volume resuscitation. Other important cardiac causes are septic emboli from bacterial endocarditis and emboli caused by atrial myxomata. The majority of AION cases occur during CPB followed by head/neck surgery and prone spine surgery. CPB is used to allow coronary artery bypass grafting on a motionless heart. It has many side-effects and complications associated with its use and we report here a case of bilateral retinal infarction during routine coronary artery bypass grafting in a young male patient with multiple risk factors for developing this complication despite steps to minimise its occurrence.

摘要

术后视力丧失是一种严重的围手术期并发症。最常见的病因是前部缺血性视神经病变(AION)、后部缺血性视神经病变(PION)和视网膜中央动脉阻塞(CRAO)。这些似乎与某些类型的手术有关,最常见的是脊柱手术和心脏搭桥手术;其余的分布在:导致大量失血的重大创伤;头部/颈部及鼻腔或鼻窦手术;重大血管手术(主动脉瘤修复、主动脉-双股动脉搭桥);普通外科手术;泌尿外科手术;妇科手术;吸脂手术;肝移植以及手术持续时间。非手术风险因素是多方面的:高龄、术后长期贫血、体位(仰卧位与俯卧位)、视网膜静脉引流改变、高血压、吸烟、动脉粥样硬化、高脂血症、糖尿病、高凝状态、低血压、失血和大量液体复苏。其他重要的心脏病因是细菌性心内膜炎引起的脓毒性栓子和心房黏液瘤引起的栓子。大多数AION病例发生在体外循环期间,其次是头颈部手术和俯卧位脊柱手术。体外循环用于在静止的心脏上进行冠状动脉搭桥术。它有许多与其使用相关的副作用和并发症,我们在此报告一例年轻男性患者在常规冠状动脉搭桥术中发生双侧视网膜梗死的病例,该患者尽管采取了措施尽量减少这种并发症的发生,但仍有多种发生此并发症的风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da4/3253690/b87b444f27a3/1749-8090-6-154-1.jpg

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