Department of Otorhinolaryngology, São João University Hospital Center, Porto, Portugal.
Department of Surgery and Physiology, Faculty of Medicine of Porto University, Porto, Portugal.
Ear Nose Throat J. 2024 Aug;103(8):NP472-NP475. doi: 10.1177/01455613211069349. Epub 2022 Jan 5.
Cutaneous metastases from squamous cell carcinomas of the head and neck region are uncommon, and their location at the nasal tip is exceptionally rare. A patient, previously treated with surgery and chemoradiation for a hypopharyngeal squamous cell carcinoma, developed several red nodular skin lesions at the nasal tip. Biopsy revealed cutaneous metastasis from the primary tumor. This manifestation was previously described as a "clown nose," given their appearance and location. Skin lesions should raise suspicion of malignancy, despite their location at uncommon places, particularly in patients with previous diagnosed cancer. Clinicians must be aware that metastases from head and neck cancer can present as a "clown nose."
头颈部鳞状细胞癌的皮肤转移并不常见，而发生在鼻尖的转移则极其罕见。一名曾因下咽鳞状细胞癌接受手术和放化疗治疗的患者，在鼻尖出现了几个红色结节性皮肤病变。活检显示为原发性肿瘤的皮肤转移。鉴于其外观和位置，这种表现以前被描述为“小丑鼻”。尽管病变发生在不常见的部位，但皮肤病变仍应引起对恶性肿瘤的怀疑，尤其是在有先前诊断为癌症的患者中。临床医生必须意识到，头颈部癌症的转移可能表现为“小丑鼻”。
