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小丑鼻:一例面部毁容性结节状鳞状细胞癌病例

Clown nose: a case of disfiguring nodular squamous cell carcinoma of the face.

作者信息

Colletti Giacomo, Allevi Fabiana, Moneghini Laura, Palvarini Marina

机构信息

San Paolo Hospital, Milan, Italy.

出版信息

BMJ Case Rep. 2014 Jan 31;2014:bcr2013200471. doi: 10.1136/bcr-2013-200471.

DOI:10.1136/bcr-2013-200471
PMID:24488659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3912395/
Abstract

'Clown nose' (CN) is the common medical term referring to a reddish-brown bulge involving the tip of the nose, reminding of a clown's fake red nose. Reports about these tumours are scarce. Most reports refer to metastatic skin manifestation of systemic malignancies: this condition has been rarely described as a primary skin neoplasm. We report a case of a 31-year-old patient with a giant cutaneous squamous cell carcinoma of the nose which evolved into a CN. After ruling out genetic or immune risk factors, the patient was treated with surgical excision of the lesion and local reconstruction with good aesthetic outcome and no recurrence over a 2-year follow-up.

摘要

“小丑鼻”(CN)是一个常见的医学术语,指鼻尖出现的红棕色隆起,让人联想到小丑的假红鼻子。关于这些肿瘤的报道很少。大多数报道涉及系统性恶性肿瘤的转移性皮肤表现:这种情况很少被描述为原发性皮肤肿瘤。我们报告一例31岁患者,患有鼻部巨大皮肤鳞状细胞癌,其演变成了“小丑鼻”。在排除遗传或免疫风险因素后,对该患者进行了病变手术切除及局部重建,美容效果良好,随访2年无复发。

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Clown nose: a case of disfiguring nodular squamous cell carcinoma of the face.小丑鼻:一例面部毁容性结节状鳞状细胞癌病例
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Indian J Dermatol. 2021 Sep-Oct;66(5):530-539. doi: 10.4103/ijd.ijd_141_21.
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Tumor of the Nose - A Rare Manifestation of a Metastatic Lung Cancer.鼻部肿瘤——转移性肺癌的一种罕见表现
Clin Cosmet Investig Dermatol. 2021 Sep 21;14:1311-1318. doi: 10.2147/CCID.S318748. eCollection 2021.
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Update of Clown Nose-Like Lesion, a Underrecognized Manifestation of Metastatic Malignancies and Genetic Cancer Predisposition Syndromes.小丑鼻样病变的最新情况,一种未被充分认识的转移性恶性肿瘤和遗传性癌症易感性综合征的表现。
Front Med (Lausanne). 2021 May 13;8:673336. doi: 10.3389/fmed.2021.673336. eCollection 2021.

本文引用的文献

1
Skin metastasis of hypopharyngeal carcinoma to the nasal tip.下咽癌鼻尖皮肤转移
Yonago Acta Med. 2013 Jun;56(2):57-8. Epub 2013 Jul 12.
2
The role of maxillary osteotomy in the treatment of arhinia.上颌骨截骨术在无鼻畸形治疗中的作用。
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Disfiguring basal cell carcinoma of the nose ("clown nose").鼻部毁容性基底细胞癌(“小丑鼻”)
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Colorectal cancer due to deficiency in DNA mismatch repair function: a review.由于 DNA 错配修复功能缺陷导致的结直肠癌:综述。
Adv Anat Pathol. 2009 Nov;16(6):405-17. doi: 10.1097/PAP.0b013e3181bb6bdc.
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[Clown nose as an initial manifestation of squamous-cell lung carcinoma].[小丑鼻作为肺鳞状细胞癌的初始表现]
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Plast Reconstr Surg. 2002 May;109(6):1839-55; discussion 1856-61. doi: 10.1097/00006534-200205000-00010.
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Cutaneous metastatic lung cancer: literature review and report of a tumor on the nose from a large cell undifferentiated carcinoma.皮肤转移性肺癌:文献综述及一例源自大细胞未分化癌的鼻部肿瘤报告
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"Clown nose" as a first manifestation of lung carcinoma.
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