小丑鼻：一例面部毁容性结节状鳞状细胞癌病例
Clown nose: a case of disfiguring nodular squamous cell carcinoma of the face.
作者信息
Colletti Giacomo, Allevi Fabiana, Moneghini Laura, Palvarini Marina
机构信息
San Paolo Hospital, Milan, Italy.
出版信息
BMJ Case Rep. 2014 Jan 31;2014:bcr2013200471. doi: 10.1136/bcr-2013-200471.
Abstract
'Clown nose' (CN) is the common medical term referring to a reddish-brown bulge involving the tip of the nose, reminding of a clown's fake red nose. Reports about these tumours are scarce. Most reports refer to metastatic skin manifestation of systemic malignancies: this condition has been rarely described as a primary skin neoplasm. We report a case of a 31-year-old patient with a giant cutaneous squamous cell carcinoma of the nose which evolved into a CN. After ruling out genetic or immune risk factors, the patient was treated with surgical excision of the lesion and local reconstruction with good aesthetic outcome and no recurrence over a 2-year follow-up.
摘要
“小丑鼻”（CN）是一个常见的医学术语，指鼻尖出现的红棕色隆起，让人联想到小丑的假红鼻子。关于这些肿瘤的报道很少。大多数报道涉及系统性恶性肿瘤的转移性皮肤表现：这种情况很少被描述为原发性皮肤肿瘤。我们报告一例31岁患者，患有鼻部巨大皮肤鳞状细胞癌，其演变成了“小丑鼻”。在排除遗传或免疫风险因素后，对该患者进行了病变手术切除及局部重建，美容效果良好，随访2年无复发。
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本文引用的文献
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2
The role of maxillary osteotomy in the treatment of arhinia.上颌骨截骨术在无鼻畸形治疗中的作用。
J Oral Maxillofac Surg. 2012 May;70(5):e361-8. doi: 10.1016/j.joms.2012.01.009. Epub 2012 Feb 23.
3
Disfiguring basal cell carcinoma of the nose ("clown nose").鼻部毁容性基底细胞癌（“小丑鼻”）
Ear Nose Throat J. 2012 Jan;91(1):E26-7. doi: 10.1177/014556131209100121.
4
Colorectal cancer due to deficiency in DNA mismatch repair function: a review.由于 DNA 错配修复功能缺陷导致的结直肠癌：综述。
Adv Anat Pathol. 2009 Nov;16(6):405-17. doi: 10.1097/PAP.0b013e3181bb6bdc.
5
[Clown nose as an initial manifestation of squamous-cell lung carcinoma].[小丑鼻作为肺鳞状细胞癌的初始表现]
Arch Bronconeumol. 2009 Jan;45(1):60-1. doi: 10.1016/j.arbres.2008.02.003. Epub 2009 Jan 3.
6
An approach to managing non-melanoma skin cancer of the nose with mucosal invasion: our experience.
Acta Otolaryngol. 2008 Aug;128(8):915-9. doi: 10.1080/00016480701760106.
7
[Excision skin margin and recurrence rate of skin cancer: a prospective study of 844 cases].[皮肤癌的手术切缘与复发率：844例前瞻性研究]
Ann Chir Plast Esthet. 2008 Oct;53(5):389-98. doi: 10.1016/j.anplas.2007.07.015. Epub 2007 Oct 24.
8
A 10-year experience in nasal reconstruction with the three-stage forehead flap.应用三期前额皮瓣进行鼻再造的10年经验
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Ear Nose Throat J. 2000 Feb;79(2):96-7, 100-1.
10
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