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一名后来被诊断为皮肌炎的患者吞咽困难的非典型表现:病例报告

Atypical Presentation of Dysphagia in a Patient Diagnosed Later With Dermatomyositis: A Case Report.

作者信息

Elmdaah Ali, Ali Abuobeida, Nadeem Zulakha, Habieb Mohamed, Pradeep John, Metangi Kevin

机构信息

Gastroenterology, Peterborough City Hospital, Peterborough, GBR.

Rheumatology, Peterborough City Hospital, Peterborough, GBR.

出版信息

Cureus. 2021 Nov 28;13(11):e19964. doi: 10.7759/cureus.19964. eCollection 2021 Nov.

Abstract

Dysphagia has been reported in 10%-73% of patients with dermatomyositis. We present the case of a 58-year-old female patient who presented to the emergency department of Peterborough City Hospital with acute-onset difficulty in swallowing. Physical examination demonstrates proximal muscle weakness of the upper limbs and symmetrical skin rash over the face, chest, and thighs. Both clinical and laboratory findings pointed towards the diagnosis dermatomyositis. Oesophagogastroduodenoscopy identified no significant abnormality reducing the possibility of dysphagia due to an intrusive lesion, such as an abscess or a malignancy. MRI scan of the lower limbs revealed evidence of proximal myositis. CT neck, chest, abdomen and pelvis exclude any associated malignancy. The patient was treated initially with intravenous pulses of methylprednisolone for three days, and then switched to oral prednisolone and cyclophosphamide cycles and was considered for intravenous immunoglobulins as her symptoms had not completely resolved.

摘要

据报道,10%-73%的皮肌炎患者存在吞咽困难。我们报告了一例58岁女性患者,她因急性吞咽困难到彼得伯勒市医院急诊科就诊。体格检查显示上肢近端肌肉无力,面部、胸部和大腿出现对称性皮疹。临床和实验室检查结果均指向皮肌炎的诊断。食管胃十二指肠镜检查未发现明显异常,排除了因脓肿或恶性肿瘤等侵入性病变导致吞咽困难的可能性。下肢MRI扫描显示近端肌炎的迹象。颈部、胸部、腹部和骨盆的CT检查排除了任何相关恶性肿瘤。患者最初接受了三天的静脉注射甲泼尼龙冲击治疗,然后改为口服泼尼松龙和环磷酰胺周期治疗,由于症状未完全缓解,考虑使用静脉注射免疫球蛋白。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/170a/8714034/c78b99290c59/cureus-0013-00000019964-i01.jpg

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