Department of Radiology, Jagiellonian University Medical College, Krakow, Poland.
Diagnostic Imaging Unit, University Hospital, Krakow, Poland.
Neurol Neurochir Pol. 2022;56(1):68-74. doi: 10.5603/PJNNS.a2022.0005. Epub 2022 Jan 5.
The aim of this study was to assess the value of dual energy computed tomography (DECT) in the differentiation of iodine contrast agent staining from secondary brain haemorrhage in patients with acute ischaemic stroke treated with mechanical thrombectomy.
The group analysed consisted of 66 hyperdense areas in 64 patients with acute ischaemic stroke treated with mechanical thrombectomy and controlled in DECT performed within the first 24 hours after thrombectomy. In every area both qualitative and quantitative analysis of iodine and water material density (MD) maps was performed for the differentiation of iodine and blood, as well as CT density analysis.
66.7% of hyperdense areas were classified as iodine, 18.2% as iodine + blood, and 15.1% as blood. The density of iodine was significantly higher in the iodine (median 9.64 100ug/cm3) group compared to the blood (median 3.97 100ug/cm3) and iodine + blood (median 7.57 100ug/cm3) groups. The density of water was significantly higher in the blood (median 1,051.50 mg/cm3) and iodine + blood (median 1,038.00 mg/cm3) groups compared to the iodine (median 1,021.00 mg/cm3) group.
DECT with iodine-water material decomposition maps is a valuable tool in the differentiation of prolonged staining of iodine contrast agent from secondary brain haemorrhage in patients with acute ischaemic stroke treated with mechanical thrombectomy. The value of 6 100ug/cm3 (0.6 mg/cm3) seems a good threshold in quantitative differentiation of iodine from blood on iodine (water) MD maps. The value of 1,030 mg/cm3 seems a good threshold in quantitative differentiation of iodine from blood on water (iodine) MD maps.
本研究旨在评估双能 CT（DECT）在区分接受机械血栓切除术治疗的急性缺血性卒中患者中碘造影剂染色与继发性脑出血的价值。
分析组包括 64 例接受机械血栓切除术治疗的急性缺血性卒中患者的 66 个高密度区，在血栓切除术后 24 小时内进行 DECT 检查。对每个区域均进行碘和水物质密度（MD）图的定性和定量分析，以区分碘和血液，并进行 CT 密度分析。
66.7%的高密度区被归类为碘，18.2%为碘+血液，15.1%为血液。碘组的碘密度明显高于血液组（中位数 9.64 100ug/cm3）和碘+血液组（中位数 7.57 100ug/cm3）。水的密度在血液组（中位数 1,051.50 mg/cm3）和碘+血液组（中位数 1,038.00 mg/cm3）中明显高于碘组（中位数 1,021.00 mg/cm3）。
DECT 结合碘-水物质分解图是一种有价值的工具，可用于区分接受机械血栓切除术治疗的急性缺血性卒中患者中碘造影剂延长染色与继发性脑出血。6 100ug/cm3（0.6 mg/cm3）的数值似乎是碘和血液在碘（水）MD 图上定量区分的良好阈值。1,030 mg/cm3 的数值似乎是碘和血液在水（碘）MD 图上定量区分的良好阈值。
