放射性直肠炎：美国死亡率及住院结局的预测因素

Radiation proctitis: predictors of mortality and inpatient outcomes in the United States.

作者信息

Dahiya Dushyant S, Kichloo Asim, Perisetti Abhilash, Shaka Hafeez, Singh Jagmeet, Inamdar Sumant

机构信息

Central Michigan University College of Medicine, Saginaw, MI (Dushyant S. Dahiya, Asim Kichloo).

Parkview Cancer Institute, Fort Wayne, IN (Abhilash Perisetti).

出版信息

Ann Gastroenterol. 2022 Jan-Feb;35(1):63-67. doi: 10.20524/aog.2021.0684. Epub 2021 Dec 11.

DOI:10.20524/aog.2021.0684

PMID:34987290

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8713349/

Abstract

BACKGROUND

We aimed to evaluate the characteristics of hospitalizations for radiation proctitis (RP).

METHODS

The National Inpatient Sample (NIS) was analyzed to identify RP hospitalizations for 2016 and 2017. Outcomes included mortality, predictors of mortality, mean length of stay (LOS), mean total hospital cost (THC), and numerous system-based complications.

RESULTS

We identified 16,810 adult hospitalizations for RP. On admission, an initial diagnosis of RP was established for only 27.54% of these patients. The mean age was 72.3±0.5 years and 30.2% of the study population was female. Whites made up 68.7% of the study population. Most hospitalizations for RP were at large (51%), urban (93.6%), and teaching (71.1%) hospitals. The inpatient mortality for RP hospitalizations was 1.7%. After adjusting for biodemographic factors, hospitalization characteristics and comorbidities, older age and protein energy malnutrition (PEM) were associated with higher odds of inpatient mortality. The mean LOS and THC for RP hospitalizations were 5.6 days and $53,800, respectively. Inpatient complications associated with RP included acute renal failure (19.7%), sepsis (4.4%), deep vein thrombosis (3.7%), acute respiratory failure (3.3%), and pulmonary embolism (0.7%).

CONCLUSIONS

Inpatient mortality for RP was 1.7%. Older age and PEM were associated with higher odds of inpatient mortality.

摘要

背景

我们旨在评估放射性直肠炎（RP）住院治疗的特征。

方法

对国家住院患者样本（NIS）进行分析，以确定2016年和2017年RP的住院病例。结局指标包括死亡率、死亡预测因素、平均住院时间（LOS）、平均总住院费用（THC）以及众多基于系统的并发症。

结果

我们确定了16810例成人RP住院病例。入院时，这些患者中仅有27.54%被初步诊断为RP。平均年龄为72.3±0.5岁，研究人群中30.2%为女性。白人占研究人群的68.7%。大多数RP住院病例发生在大型（51%）、城市（93.6%）和教学（71.1%）医院。RP住院患者的住院死亡率为1.7%。在对生物人口统计学因素、住院特征和合并症进行调整后，年龄较大和蛋白质能量营养不良（PEM）与住院死亡率较高的几率相关。RP住院病例的平均LOS和THC分别为5.6天和53800美元。与RP相关的住院并发症包括急性肾衰竭（19.7%）、脓毒症（4.4%）、深静脉血栓形成（3.7%）、急性呼吸衰竭（3.3%）和肺栓塞（0.7%）。