Saoud Carla, Wangsiricharoen Sintawat, Kahler Jessica, Maleki Zahra
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Diagn Cytopathol. 2022 Apr;50(4):154-161. doi: 10.1002/dc.24913. Epub 2022 Jan 5.
The term "Atypia" has been employed to describe a wide spectrum of cytomorphologic features associated with reactive/inflammatory processes as well as those suspicious for neoplasms in cytology. Similar to other cytopathology reporting systems, the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has reserved the atypical category for cytology specimens lacking quantitative and/or qualitative cytomorphologic features to be diagnosed with confidence as either non-neoplastic or neoplastic. In MSRSGC, the atypical category is associated with a risk of malignancy and recommendation for clinical management. In this review, we discuss the value of atypical diagnostic category of MSRSGC in both cystic and non-cystic salivary gland lesions by evaluating our institutional case cohort.
术语“非典型性”已被用于描述一系列与反应性/炎症性过程相关的细胞形态学特征，以及细胞学中那些疑似肿瘤的特征。与其他细胞病理学报告系统类似，米兰唾液腺细胞病理学报告系统（MSRSGC）将非典型类别保留用于那些缺乏定量和/或定性细胞形态学特征的细胞学标本，这些标本无法明确诊断为非肿瘤性或肿瘤性。在MSRSGC中，非典型类别与恶性风险及临床管理建议相关。在本综述中，我们通过评估我们机构的病例队列，讨论MSRSGC非典型诊断类别在囊性和非囊性唾液腺病变中的价值。
