Tucci Marisa, Crighton Gemma, Goobie Susan M, Russell Robert T, Parker Robert I, Haas Thorsten, Nellis Marianne E, Vogel Adam M, Lacroix Jacques, Stricker Paul A
Department of Pediatrics, Sainte-Justine University Hospital, University of Montreal, Montreal, QC, Canada.
Department of Haematology, Royal Children's Hospital, Melbourne, VIC, Australia.
Pediatr Crit Care Med. 2022 Jan 1;23(13 Supple 1 1S):e50-e62. doi: 10.1097/PCC.0000000000002858.
To present consensus statements and supporting literature for plasma and platelet transfusions in critically ill children following noncardiac surgery and critically ill children undergoing invasive procedures outside the operating room from the Transfusion and Anemia EXpertise Initiative - Control/Avoidance of Bleeding.
Systematic review and consensus conference of international, multidisciplinary experts in platelet and plasma transfusion management of critically ill children.
Not applicable.
Critically ill children undergoing invasive procedures outside of the operating room or noncardiac surgery.
None.
A panel of 10 experts developed evidence-based and, when evidence was insufficient, expert-based statements for plasma and platelet transfusions in critically ill children following noncardiac surgery or undergoing invasive procedures outside of the operating room. These statements were reviewed and ratified by the 29 Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding experts. A systematic review was conducted using MEDLINE, EMBASE, and Cochrane Library databases, from inception to December 2020. Consensus was obtained using the Research and Development/University of California, Los Angeles Appropriateness Method. Results were summarized using the Grading of Recommendations Assessment, Development, and Evaluation method. We developed eight expert consensus statements focused on the critically ill child following noncardiac surgery and 10 expert consensus statements on the critically ill child undergoing invasive procedures outside the operating room.
Evidence regarding plasma and platelet transfusion in critically ill children in this area is very limited. The Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding Consensus Conference developed 18 pediatric specific consensus statements regarding plasma and platelet transfusion management in these critically ill pediatric populations.
呈现来自输血与贫血专业倡议——控制/避免出血方面关于非心脏手术后危重症儿童以及在手术室以外接受侵入性操作的危重症儿童血浆和血小板输注的共识声明及相关支持文献。
对危重症儿童血小板和血浆输注管理方面的国际多学科专家进行系统综述和共识会议。
不适用。
在手术室以外接受侵入性操作或进行非心脏手术的危重症儿童。
无。
一个由10名专家组成的小组针对非心脏手术后危重症儿童或在手术室以外接受侵入性操作的危重症儿童的血浆和血小板输注制定了基于证据的声明，在证据不足时则基于专家意见制定声明。这些声明由29名输血与贫血专业倡议——控制/避免出血专家进行了审查和批准。使用MEDLINE、EMBASE和Cochrane图书馆数据库进行了从创建到2020年12月的系统综述。采用加利福尼亚大学洛杉矶分校研发适用性方法达成共识。结果使用推荐分级评估、制定和评价方法进行总结。我们制定了8项针对非心脏手术后危重症儿童的专家共识声明以及10项针对在手术室以外接受侵入性操作的危重症儿童的专家共识声明。
该领域关于危重症儿童血浆和血小板输注的证据非常有限。输血与贫血专业倡议——控制/避免出血共识会议针对这些危重症儿童群体的血浆和血小板输注管理制定了18项儿科特定的共识声明。
