Department of Radiology, Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey.
Department of Radiology, Ministry of Health Ankara City Hospital, Ankara, Turkey.
Br J Radiol. 2022 Apr 1;95(1132):20210832. doi: 10.1259/bjr.20210832. Epub 2022 Jan 7.
Our single-center retrospective study aimed to evaluate the relationship between magnetic resonance (MR)-directed ultrasound (MDUS) detectability and MRI findings of non-mass enhancement (NME) lesions, regarding the morphologic and enhancement features, the distance from the skin and nipple, and the presence of concomitant landmarks.
A total of 350 MRI-detected NME lesions that were determined between January 2015 and May 2019 and subsequently underwent MDUS were analyzed. The MRI findings, biopsy results, and follow-up outcomes of lesions were recorded. The correlation between the MRI findings of the lesions and MDUS detectability was analyzed.
114 (32.6%) of the 350 lesions had a counterpart in the MDUS. Respectively, 66 (37.9%), 38 (43.2%) and 59 (38.3%) of the lesions detected in MDUS were larger than 20 mm in size, with a distance of less than 20 mm to the nipple and 15 mm to the skin. The lesion size and lesion distance to the nipple and skin were significantly associated with a ultrasound correlate ( < 0.05). The MDUS detection rate was significantly higher in NME lesions with MR findings including diffuse distribution ( < 0.001), clustered-ring enhancement pattern ( < 0.001), washout kinetic curve ( = 0.006), and MR-BIRADS category 5 ( < 0.001). Multivariate logistic regression showed that only the clustered-ring enhancement pattern was significantly associated with an MDUS correlation ( < 0.001).
Statistically significant correlations were found between the size, distance to the nipple and skin, distribution pattern, enhancement pattern and kinetic curve of the NME lesions on MRI and ultrasound detectability.
We found that clustered-ring enhancement patterns were significantly more frequent in MR-directed ultrasound detectable lesions.
我们的单中心回顾性研究旨在评估磁共振（MR）引导超声（MDUS）可检测性与非肿块强化（NME）病变的 MRI 表现之间的关系，包括形态和强化特征、距皮肤和乳头的距离以及伴随标志的存在。
分析了 2015 年 1 月至 2019 年 5 月间经 MRI 检测并随后进行 MDUS 的 350 例 NME 病变。记录了病变的 MRI 结果、活检结果和随访结果。分析了病变的 MRI 表现与 MDUS 可检测性之间的相关性。
350 例病变中有 114 例（32.6%）在 MDUS 中有对应物。分别有 66（37.9%）、38（43.2%）和 59（38.3%）例在 MDUS 中检测到的病变大于 20mm，距乳头小于 20mm，距皮肤 15mm。病变大小、病变距乳头和皮肤的距离与超声相关性显著相关（<0.05）。MR 表现为弥漫性分布（<0.001）、簇状环形强化模式（<0.001）、洗脱动力学曲线（=0.006）和 MR-BIRADS 分类 5（<0.001）的 NME 病变的 MDUS 检测率显著较高。多变量逻辑回归显示，只有簇状环形强化模式与 MDUS 相关性显著相关（<0.001）。
NME 病变的大小、距乳头和皮肤的距离、分布模式、强化模式和动力学曲线与 MRI 和超声可检测性之间存在显著的相关性。
我们发现簇状环形强化模式在 MR 引导超声可检测病变中更为常见。
