Matteussi Giovanna Teixeira, Jacometti Victor, Franco Ademir, da Silva Ricardo Henrique Alves
Department of Pathology and Legal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto. Av. Bandeirantes, 3900 - Vila Virginia, Ribeirão Preto, SP 14015-130, Brazil.
Centre of Forensic Medicine and Dentistry, School of Dentistry, University of Dundee, Nethergate, DD1 4HN Dundee, Scotland, UK; Department of Therapeutic Dentistry, Sechenov University, Moscow. Bolshaya Pirogovskaya Ulitsa 19, Moscow, 119146, Russia; Department of Forensic Dentistry, Faculdade São Leopoldo Mandic, Campinas. R. Jose Rocha Junqueira, 13, Swift, Campinas, SP 13045-755, Brazil.
Forensic Sci Int. 2022 Feb;331:111154. doi: 10.1016/j.forsciint.2021.111154. Epub 2021 Dec 20.
Teeth are considered the most resistant structures in the human body. In forensic odontology, teeth are useful for human identification, especially when dental age estimation is necessary. Despite numerous studies, there is no consensus regarding the best methods for dental age estimation. The analysis of aspartic acid racemization, however, has shown promising results. This scoping review aimed to present a descriptive synthesis of the current literature regarding dental age estimation through aspartic acid racemization. Four electronic databases were screened: PubMed, Scielo, Web of Science, and Scopus. Cross-sectional studies published before April 2021 were selected. From 206 articles found, 26 met the eligibility criteria. Several experimental protocols and laboratory settings were detected, but the different protocols did not seem to significantly reduce error rates in dental age estimation. The analysis of aspartic acid racemization in human dental tissues produced accurate and potentially reliable results for age estimation. Aspartic acid racemization stands out especially in the adulthood - age category in which other methods struggle to deliver proper performances. Studies with larger samples, independent testing, and standardized laboratory procedures are necessary. Equator-like reporting guidelines are encouraged to enable future systematic reviews and meta-analyses.
牙齿被认为是人体中最具抗性的结构。在法医牙科学中，牙齿对人类身份识别很有用，尤其是在需要估计牙龄的时候。尽管有大量研究，但关于牙龄估计的最佳方法尚无共识。然而，天冬氨酸消旋化分析已显示出有希望的结果。本综述旨在对当前有关通过天冬氨酸消旋化进行牙龄估计的文献进行描述性综合。筛选了四个电子数据库：PubMed、Scielo、科学网和Scopus。选择了2021年4月之前发表的横断面研究。从找到的206篇文章中，26篇符合纳入标准。检测到了几种实验方案和实验室设置，但不同的方案似乎并没有显著降低牙龄估计中的错误率。对人类牙齿组织中天冬氨酸消旋化的分析为年龄估计产生了准确且可能可靠的结果。天冬氨酸消旋化在成年年龄类别中尤为突出，在该类别中其他方法难以取得良好效果。需要进行更大样本量、独立测试和标准化实验室程序的研究。鼓励采用类似赤道原则的报告指南，以便未来进行系统评价和荟萃分析。
