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乳腺放射治疗中不规则表面补偿器和调强放射治疗的剂量学评估

Dosimetric evaluation of irregular surface compensator and intensity-modulated radiotherapy in breast radiotherapy.

作者信息

Inan Gokcen, Gul Osman Vefa, Basaran Hamit

机构信息

Department of Keykubat Campus, Faculty of Radiation Oncology, Selouk University, Konya, Turkey.

出版信息

Rep Pract Oncol Radiother. 2021 Dec 30;26(6):984-989. doi: 10.5603/RPOR.a2021.0121. eCollection 2021.

DOI:10.5603/RPOR.a2021.0121
PMID:34992872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8726430/
Abstract

BACKGROUND

This dosimetric study aims to evaluate the dosimetric advantage of the irregular surface compensator (ISC) compared with the intensity-modulated radiotherapy (IMRT).

MATERIALS AND METHODS

Ten patients with whole breast irradiation were planned with the ISC and IMRT techniques. Six different beam directions were selected for IMRT and ISC plans. The treatment plans were evaluated with respect to planning target coverage, dose homogeneity index (DHI) and organs at risk (OARs) sparing. Monitor units (MUs) and the delivery time were analysed for treatment efficiency.

RESULTS

The ISC technique provides a better coverage of the PTV and statistically significantly better homogeneity of the dose distribution. For the ipsilateral lung and heart, ISC and IMRT techniques deliver almost the same dose in all plans. However, MU counts and delivery time were significantly lower with the IMRT technique (p < 0.05).

CONCLUSION

For breast radiotherapy, when the ISC method was compared to the IMRT method, ISC provided better dose distribution for the target.

摘要

背景

本剂量学研究旨在评估不规则表面补偿器(ISC)与调强放射治疗(IMRT)相比的剂量学优势。

材料与方法

对10例全乳照射患者采用ISC和IMRT技术进行计划制定。为IMRT和ISC计划选择六个不同的射野方向。从计划靶区覆盖、剂量均匀性指数(DHI)和危及器官(OARs)保护方面对治疗计划进行评估。分析监测单位(MUs)和照射时间以评估治疗效率。

结果

ISC技术能更好地覆盖计划靶区(PTV),且剂量分布的均匀性在统计学上显著更好。对于同侧肺和心脏,ISC和IMRT技术在所有计划中给予的剂量几乎相同。然而,IMRT技术的MU计数和照射时间显著更低(p < 0.05)。

结论

对于乳腺癌放疗,将ISC方法与IMRT方法相比时,ISC为靶区提供了更好的剂量分布。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d0f/8726430/33107e1594d3/rpor-26-6-984f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d0f/8726430/8137aa5dad90/rpor-26-6-984f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d0f/8726430/33107e1594d3/rpor-26-6-984f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d0f/8726430/8137aa5dad90/rpor-26-6-984f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d0f/8726430/33107e1594d3/rpor-26-6-984f2.jpg

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本文引用的文献

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Dosimetric Comparison of Irregular Surface Compensator and Field-in-Field for Whole Breast Radiotherapy.全乳放疗中不规则表面补偿器与子野技术的剂量学比较
J Med Phys. 2018 Apr-Jun;43(2):79-84. doi: 10.4103/jmp.JMP_73_17.
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Integrated skin flash planning technique for intensity-modulated radiation therapy for vulvar cancer prevents marginal misses and improves superficial dose coverage.用于外阴癌调强放射治疗的集成皮肤闪光计划技术可防止边缘遗漏并改善浅表剂量覆盖。
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Performance of the irregular surface compensator compared with four-field box and intensity modulated radiation therapy for gynecologic cancer.
不规则表面补偿器与四野盒式照射及调强放射治疗在妇科癌症治疗中的性能比较
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Improvement of dose distribution with irregular surface compensator in whole breast radiotherapy.全乳放疗中使用不规则表面补偿器改善剂量分布。
J Med Phys. 2013 Jul;38(3):115-9. doi: 10.4103/0971-6203.116361.
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The dosimetric impact of respiratory breast movement and daily setup error on tangential whole breast irradiation using conventional wedge, field-in-field and irregular surface compensator techniques.常规楔形野、内野加和非规则表面补偿器技术在切线野全乳腺照射中呼吸运动和日常摆位误差的剂量学影响。
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Dosimetry tools and techniques for IMRT.调强适形放疗的剂量学工具和技术。
Med Phys. 2011 Mar;38(3):1313-38. doi: 10.1118/1.3514120.
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Different intensity extension methods and their impact on entrance dose in breast radiotherapy: A study.不同强度延伸方法及其对乳腺癌放疗中入射剂量的影响:一项研究。
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Irregular surface compensation for radiotherapy of the breast: correlating depth of the compensation surface with breast size and resultant dose distribution.用于乳房放射治疗的不规则表面补偿:补偿表面的深度与乳房大小及相应的剂量分布的相关性。
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