Hernández R E, Cardonnet L J, Libman C, Gagliardino J J
Centro de Endocrinologia Experimental y Aplicada (UNLP-CONICET), Facultad de Ciencias Médicas, La Plata, Argentina.
Diabetes Res Clin Pract. 1987 Sep-Oct;3(5):277-83. doi: 10.1016/s0168-8227(87)80051-7.
The prevalence of diabetes mellitus and obesity was studied in the urban area of La Plata City, Argentina. In the chosen population the age ranged from 20 to 74 years. Overt diabetics were not included in the study. For each individual, sex, age, weight, height, body mass index, (BMI), education, type of job and clinical and diabetic background were registered. Plasma glucose values were measured by reading Dextrostix strips in the Dextrometer, in samples obtained by finger punction 2 h after a 50-g glucose load. The final size of the sample (809 people), with an age and sex distribution similar to that of the general population, was attained at random, considering a diabetes prevalence of 6% in the population and a precision and confidence limit in the estimation of 2% and 95%, respectively. The results were evaluated using the post-load glucose values recommended by the World Health Organization (WHO) (200 mg/100 ml). According to these values, the prevalence of diabetes in our population was 2.7%. When adding the 2.3% of known diabetics to these figures, a prevalence of 5% was obtained. The value of the ratio of number of normal newborns/number of pregnancies significantly diminished as a function of the increment in the plasma glucose values found in the probands. Taking into account the BMI values, 37% of our sample population were obese subjects. Even when the glucose values obtained in obese subjects were within the normal range, they were significantly higher than those obtained in the nonobese group.(ABSTRACT TRUNCATED AT 250 WORDS)
对阿根廷拉普拉塔市市区的糖尿病和肥胖症患病率进行了研究。在选定人群中,年龄范围为20至74岁。显性糖尿病患者未纳入该研究。记录了每个个体的性别、年龄、体重、身高、体重指数(BMI)、教育程度、工作类型以及临床和糖尿病背景。通过在血糖仪中读取Dextrostix试纸条来测量血浆葡萄糖值,样本是在50克葡萄糖负荷后2小时通过手指穿刺获得的。考虑到人群中糖尿病患病率为6%,估计的精度和置信限分别为2%和95%,随机选取了最终样本量(809人),其年龄和性别分布与一般人群相似。使用世界卫生组织(WHO)推荐的负荷后血糖值(200毫克/100毫升)对结果进行评估。根据这些值,我们人群中的糖尿病患病率为2.7%。将已知糖尿病患者的2.3%加到这些数字中,患病率为5%。先证者血浆葡萄糖值升高时,正常新生儿数量/妊娠数量的比值显著降低。考虑到BMI值,我们样本人群中有37%为肥胖者。即使肥胖者的血糖值在正常范围内,也显著高于非肥胖组。(摘要截断于250字)