Yan Tian-Bao, Huang Jia-Qi, Huang Shi-Yun, Ahir Bhavesh K, Li Long-Man, Mo Zeng-Nan, Zhong Jian-Hong
Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.
Center for Genomics and Personalized Medicine, Guangxi Key Laboratory for Genomics and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomics and Personalized Medicine, Guangxi Medical University, Nanning, China.
Front Oncol. 2021 Dec 21;11:801173. doi: 10.3389/fonc.2021.801173. eCollection 2021.
Pancreatic cancer refers to the development of malignant tumors in the pancreas: it is associated with high mortality rates and mostly goes undetected in its early stages for lack of symptoms. Currently, surgical treatment is the only effective way to improve the survival of pancreatic cancer patients. Therefore, it is crucial to diagnose the disease as early as possible in order to improve the survival rate of patients with pancreatic cancer. Liquid biopsy is a unique diagnostic technique offering the advantage of earlier detection of tumors. Although liquid biopsies have shown promise for screening for certain cancers, whether they are effective for early diagnosis of pancreatic cancer is unclear. Therefore, we reviewed relevant literature indexed in PubMed and collated updates and information on advances in the field of liquid biopsy with respect to the early diagnosis of pancreatic cancer.
它与高死亡率相关,并且由于缺乏症状,在早期大多未被发现。目前,手术治疗是提高胰腺癌患者生存率的唯一有效方法。因此,尽早诊断该疾病对于提高胰腺癌患者的生存率至关重要。液体活检是一种独特的诊断技术,具有早期检测肿瘤的优势。尽管液体活检在某些癌症的筛查中显示出前景,但它们对胰腺癌早期诊断是否有效尚不清楚。因此,我们回顾了PubMed中索引的相关文献,并整理了关于液体活检领域在胰腺癌早期诊断方面的进展的最新信息。