Tamirisa Kamala P, Al-Khatib Sana M, Mohanty Sanghamitra, Han Janet K, Natale Andrea, Gupta Dhiraj, Russo Andrea M, Al-Ahmad Amin, Gillis Anne M, Thomas Kevin L
Texas Cardiac Arrhythmia Institute, Austin/Dallas, Texas, USA.
Division of Cardiology, Duke University Medical Centre, Durham, North Carolina, USA.
CJC Open. 2021 Sep 13;3(12 Suppl):S137-S148. doi: 10.1016/j.cjco.2021.09.004. eCollection 2021 Dec.
Atrial fibrillation (AF) is the most common clinical arrhythmia, and it results in adverse outcomes and increased healthcare costs. Racial and ethnic differences in AF management, although recognized, are poorly understood. This review summarizes racial differences in AF epidemiology, genetics, clinical presentation, and management. In addition, it highlights the underrepresentation of racial and ethnic populations in AF clinical trials, especially trials focused on stroke prevention. Specific strategies are proposed for future research and initiatives that have potential to eliminate racial and ethnic differences in the care of patients with AF. Addressing racial and ethnic disparities in healthcare access, enrollment in clinical trials, resource allocation, prevention, and management will likely narrow the gaps in the care and outcomes of racial and ethnic minorities suffering from AF.
心房颤动（AF）是最常见的临床心律失常，会导致不良后果并增加医疗成本。尽管人们已经认识到房颤管理中存在种族和民族差异，但对此了解甚少。本综述总结了房颤在流行病学、遗传学、临床表现和管理方面的种族差异。此外，它还强调了种族和民族人群在房颤临床试验中的代表性不足，尤其是在专注于预防中风的试验中。针对未来的研究和举措提出了具体策略，这些研究和举措有可能消除房颤患者护理中的种族和民族差异。解决医疗保健获取、临床试验入组、资源分配、预防和管理方面的种族和民族差异，可能会缩小患有房颤的种族和少数民族在护理和治疗结果方面的差距。
