Badi Niharika, Cruz-Monserrate Zobeida
Department of Internal Medicine, Division of Gastroenterology, Hepatology, and Nutrition, and Arthur G. James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Methods Mol Biol. 2022;2435:195-201. doi: 10.1007/978-1-0716-2014-4_14.
Obesity is a major risk factor for the development of multiple cancers. In efforts to develop models that will assist the scientific community in studying the mechanisms of this risk, a diet-induced obesity model of obesity is often utilized. Here we describe the use of diet-induced obesity (DIO) diets to study the effects of high-fat diet weight gain in the context of cancer mouse models.
肥胖是多种癌症发生的主要风险因素。为了开发有助于科学界研究这种风险机制的模型，人们经常使用饮食诱导肥胖模型。在此，我们描述了在癌症小鼠模型背景下，使用饮食诱导肥胖（DIO）饮食来研究高脂饮食体重增加的影响。
